Arthritis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
CIA was induced in DBA/1J mice.Arthritic mice were treated with bosentan (100 mg/kg) once a day, starting from the day when arthritis was clinically detectable.
|
22249931 |
2012 |
Arthritis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Localization of non-Mhc collagen-induced arthritis susceptibility loci in DBA/1j mice.
|
10051620 |
1999 |
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Exogenous GH administration in arthritic DBA/1J mice reduced the severity of established CIA as well as the inflammatory environment, which also shows a GH effect on arthritis progression.
|
29887869 |
2018 |
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Mice with DBA/1JJmsSlc collagen-induced arthritis were treated with inhibitors or neutralizing antibodies.
|
29698950 |
2018 |
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
DBA/1J mice with CIA that received IL-17-/- donor bone marrow showed potently inhibited development and severity of clinical arthritis as compared with CIA mice that received WT bone marrow.
|
23114425 |
2012 |
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Exposure of leukocytes from type II collagen-immunized DBA/1 mice to ibudilast in vitro attenuated their ability to adoptively transfer arthritis to DBA/1J-Prkdc<sup>SCID</sup> mice, providing evidence of an immunomodulatory effect.
|
30474934 |
2019 |
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Interestingly, NSC23766 alleviated the process of collagen-induced arthritis of DBA mice in vivo, including the reduced hind paw thickness and ankle stiffness, the reduction of arthritic scores and incidence of arthritis.
|
30880553 |
2020 |
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
To find an "unlimited" source of antigenic material (aggrecan) for arthritis induction in BALB/c mice; to analyze the specificities of immune reactions to aggrecan and type II collagen in 2 arthritis-susceptible murine strains, BALB/c mice for proteoglycan (aggrecan)-induced arthritis and DBA/1j mice for collagen-induced arthritis; to compare the histopathologic features of arthritis induced by purified aggrecans or total extracts of osteoarthritic (OA) cartilage; and to determine arthritis susceptibility in various BALB/c colonies.
|
9627010 |
1998 |
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Alpha-mangostin: Anti-inflammatory and antioxidant effects on established collagen-induced arthritis in DBA/1J mice.
|
30557668 |
2019 |
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
In contrast to the situation in humans, lpxL1 LPS has agonistic activity for cytokine production in peritoneal macrophages of DBA mice, and exacerbated arthritis in murine collagen induced arthritis model.
|
21088052 |
2011 |
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
DBA/1JJmsSlc control mice (n = 5) and DBA/1JJmsSlc collagen-induced arthritis mouse model (arthritis mice; n = 5) were used.
|
28573874 |
2018 |
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
In this study, we investigated the improvement of astilbin and low-dose MTX combination on collagen-induced arthritis in DBA/1J mice.
|
29410374 |
2018 |
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
A mouse model of DBA/1JJmsSlc collagen-induced arthritis was treated with Th2 or Th17 cell inhibitor, and transepidermal water loss (TEWL) and the expression of markers associated with allergic reaction and inflammation were evaluated.
|
30828078 |
2019 |
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
To induce arthritis in mice, rYKL-39 (1, 10 or 50 g in Freund's incomplete adjuvant) was injected into the right footpad of mice from four different strains (BALB/c, DBA/1J, C57BL/6 and ICR).
|
12102470 |
2003 |
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
MHC class II derived recombinant T cell receptor ligands protect DBA/1LacJ mice from collagen-induced arthritis.
|
18178865 |
2008 |
Arthritis
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Using a panel of immunohistochemical and immunofluorescence analyses in a CIA model established in 18 DBA/1J mice, we demonstrated that IL-35 promotes synoviocyte apoptosis and alternative activation of macrophages to alleviate arthritis in vivo.
|
30834683 |
2019 |
Arthritis
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The results showed that LCA significantly suppressed arthritis via the activation of SQSTM1 (p62)/nuclear factor-erythroid 2-related factor 2 (Nrf2) signaling in the collagen-induced arthritis (CIA) model of DBA mice.
|
29233793 |
2018 |