CASP8, caspase 8, 841

N. diseases: 480; N. variants: 32
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.320 AlteredExpression group BEFREE Adenocarcinomas derived from the lung in addition to high caspase-8 expression are characterized by increased expression of DR4 compared with adjacent non-neoplastic tissues. 23470529 2013
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.320 Biomarker group CTD_human Association between polymorphisms in cancer-related genes and early onset of esophageal adenocarcinoma. 21472143 2011
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.320 Biomarker group BEFREE These results suggest that Adv-caspase-8 may be a good combination partner of TRAIL and enables TRAIL to be a more potent anticancer agent in a wide range of adenocarcinoma cells which demonstrate low expression of caspase-8. 15645141 2005