CASP8, caspase 8, 841

N. diseases: 480; N. variants: 32
Disease: Acute Promyelocytic Leukemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023487
Disease: Acute Promyelocytic Leukemia
Acute Promyelocytic Leukemia 		0.010 Biomarker disease BEFREE Taken together, these findings indicate that 23-HUA induces apoptosis in HL-60 human promyelocytic leukemia cells through formation of DISC and caspase-8 activation leading to loss of <i>ΔΨ<sub>m</sub></i> and caspase-3 activation. 30551620 2018