CASP8, caspase 8, 841

N. diseases: 480; N. variants: 32
Disease: Lung Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.350 Biomarker group CTD_human A six-nucleotide insertion-deletion polymorphism in the CASP8 promoter is associated with susceptibility to multiple cancers. 17450141 2007
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.350 GeneticVariation group LHGDN Polymorphisms in the caspase-8 gene and the risk of lung cancer. 16938569 2006
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.350 AlteredExpression group LHGDN Safrole oxide induces apoptosis by activating caspase-3, -8, and -9 in A549 human lung cancer cells. 16242324 2006
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.350 Biomarker group BEFREE CASP8 may function as a tumor suppressor gene in neuroendocrine lung tumors. 12170765 2002
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.350 Biomarker group BEFREE Methylation of the key apoptosis-related gene caspase 8 (CASP8) has been reported in some childhood tumors and in neuroendocrine lung tumors. 12384554 2002
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.350 GeneticVariation group LHGDN Alterations of Fas-pathway genes associated with nodal metastasis in non-small cell lung cancer. 12037669 2002