CASP8, caspase 8, 841

N. diseases: 480; N. variants: 32
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027055
Disease: Myocardial Reperfusion Injury
Myocardial Reperfusion Injury
0.500 Biomarker phenotype CTD_human Minocycline inhibits caspase activation and reactivation, increases the ratio of XIAP to smac/DIABLO, and reduces the mitochondrial leakage of cytochrome C and smac/DIABLO. 14998631 2004
CUI: C0027055
Disease: Myocardial Reperfusion Injury
Myocardial Reperfusion Injury
0.500 Biomarker phenotype RGD Different signaling pathways induce apoptosis in endothelial cells and cardiac myocytes during ischemia/reperfusion injury. 11934844 2002