|
Adenocarcinoma of pancreas
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Hcc-1 cDNA level was increased in pancreatic adenocarcinoma.
|
11356193 |
2001 |
|
Breast Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
However, the role of SARNP in mRNA splicing and export and in the progression of breast cancer, especially of TNBC, remains unknown.
|
31313837 |
2020 |
|
Carcinoma of lung
|
0.020 |
Biomarker
|
disease |
BEFREE |
Our data suggest that overexpression of HCC1/CAPERα may increase the proliferation and migration of NSCLC cells, and HCC1/CAPERα could be a promising biomarker for lung cancer.
|
24643682 |
2014 |
|
Carcinoma of lung
|
0.020 |
Biomarker
|
disease |
BEFREE |
When cutoff values were set as mean optical density values plus 3 standard deviation of normal controls, the positive rate of autoantibodies against four tumor-associated antigens (Survivin, Cyclin B1, HCC1, and p53) reached 32%, 20%, 22%, and 18%, with area under the curve values of 0.653, 0.767, 0.622, and 0.623 in sera from 50 lung cancer, respectively (all p < 0.05).
|
29022480 |
2017 |
|
Cholangiocarcinoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
The 15-patient cohort (17 cases from 2015 to 2018) included those diagnosed with liver tumors (14 hepatocellular carcinoma, 1 cholangiocarcinoma, 1 renal-cell carcinoma, and 1 metastatic colorectal carcinoma) and chosen for radioembolization via a multimodal approach.
|
31155499 |
2019 |
|
Cholangiocarcinoma
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Of the enrolled patients, 2 were diagnosed with hepatocellular carcinoma, 1 with cholangiocellular carcinoma, 1 with liver metastasis, 2 with pancreatic ductal adenocarcinoma, 1 with renal cell carcinoma and 1 with malignant lymphoma.
|
29042975 |
2017 |
|
Cholangitis, Sclerosing
|
0.010 |
Biomarker
|
disease |
BEFREE |
Eight patients had died at the time of their entry into the Registry; 2 of pneumonia (1 P. carinii and 1 cytomegalovirus), 2 of encephalitis (1 ECHO virus and 1 cytomegalovirus), 2 of malignancy (both hepatocellular carcinoma), 1 of sclerosing cholangitis caused by Cryptosporidium, and 1 of hemolytic uremic syndrome.
|
14663287 |
2003 |
|
Cholestatic hepatitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
In this cohort, 35 patients (18.7%) were HCV core antigen (Ag)-positive, and 13 of them (37.1%) died (due to liver cirrhosis (4 cases), hepatocellular carcinoma (1 case), fibrosing cholestatic hepatitis due to HCV (1 case), and infections complicated with chronic hepatitis (6 cases)).
|
28357506 |
2017 |
|
Chronic kidney disease stage 5
|
0.010 |
Biomarker
|
disease |
BEFREE |
A novel CC chemokine, HCC-1, was isolated from the hemofiltrate of patients with chronic renal failure.
|
8551235 |
1996 |
|
Chronic Kidney Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
A novel CC chemokine, HCC-1, was isolated from the hemofiltrate of patients with chronic renal failure.
|
8551235 |
1996 |
|
Coronary heart disease
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
This study examined polymorphisms at the loci HLA-DQB1, HLA-DRB1, TNFa microsatellite, and D6S89, all which lie within or telomeric to the major histocompatibility complex (MHC) and the apolipoprotein E (APOE) and THO-1 loci in premenopausal African-American women (AAW) for their association with known coronary heart disease (CHD) risk factors.
|
15825968 |
2005 |
|
Delirium
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Among primates, a tyrosine hydroxylase (THO1) intron STR, previously implicated in both schizophrenia and drug withdrawal delirium, exhibited frequent replacements.
|
15656986 |
2005 |
|
Esophageal carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
A total of 7 studies, which included 3 studies for breast cancer, 2 for colorectal cancer, 1 for hepatocellular carcinoma, 1 for esophageal cancer and 1 for Non-Hodgkin lymphoma.
|
25524946 |
2015 |
|
Esophageal Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
A total of 7 studies, which included 3 studies for breast cancer, 2 for colorectal cancer, 1 for hepatocellular carcinoma, 1 for esophageal cancer and 1 for Non-Hodgkin lymphoma.
|
25524946 |
2015 |
|
Hepatitis B
|
0.010 |
Biomarker
|
disease |
BEFREE |
Evaluation of serum samples with different status of HBV and HCV infections suggested that HCc(1-98) might be suitable for the determination of antibodies against HCV core protein, while HBcPreS1PreS2HCc(1-98) might be of value to detect HCV and/or HBV infection in donated blood in HBV low-prevalence countries.
|
9892392 |
1999 |
|
Hepatitis C
|
0.020 |
Biomarker
|
disease |
BEFREE |
In this cohort, 35 patients (18.7%) were HCV core antigen (Ag)-positive, and 13 of them (37.1%) died (due to liver cirrhosis (4 cases), hepatocellular carcinoma (1 case), fibrosing cholestatic hepatitis due to HCV (1 case), and infections complicated with chronic hepatitis (6 cases)).
|
28357506 |
2017 |
|
Hepatitis C
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Evaluation of serum samples with different status of HBV and HCV infections suggested that HCc(1-98) might be suitable for the determination of antibodies against HCV core protein, while HBcPreS1PreS2HCc(1-98) might be of value to detect HCV and/or HBV infection in donated blood in HBV low-prevalence countries.
|
9892392 |
1999 |
|
Hepatocarcinogenesis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Collectively, these results indicate that LEF1-upregulated miR-HCC1 functions as an oncogene through the negative regulation of NFIX expression, which links the LEF1/miR-HCC1/NFIX axis to contribute to cell proliferation, migration and invasion of HCC cells and could provide novel insights into miRNA function and hepatocarcinogenesis and potential biomarkers for HCC.
|
29472529 |
2018 |
|
Kidney Failure, Chronic
|
0.010 |
Biomarker
|
disease |
BEFREE |
A novel CC chemokine, HCC-1, was isolated from the hemofiltrate of patients with chronic renal failure.
|
8551235 |
1996 |
|
Liver carcinoma
|
0.040 |
Biomarker
|
disease |
BEFREE |
The predictors (autoantibodies to HCC1, P16, P53, P90, and survivin) indicated the presence of HCC prior to diagnosis in 16 of the 17 patients, at a median lead time of 0.75 year.
|
29497780 |
2018 |
|
Liver carcinoma
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
We measured PCDH18 expression level in eight HCC cell lines as well as HCC1 and HCC2 by real-time quantitative RT-PCR.
|
29075151 |
2017 |
|
Liver carcinoma
|
0.040 |
Biomarker
|
disease |
BEFREE |
Collectively, these results indicate that LEF1-upregulated miR-HCC1 functions as an oncogene through the negative regulation of NFIX expression, which links the LEF1/miR-HCC1/NFIX axis to contribute to cell proliferation, migration and invasion of HCC cells and could provide novel insights into miRNA function and hepatocarcinogenesis and potential biomarkers for HCC.
|
29472529 |
2018 |
|
Liver carcinoma
|
0.040 |
Biomarker
|
disease |
BEFREE |
A novel protein, Hcc-1, was identified by analysis of the hepatocellular carcinoma (HCC)-M cell proteome.
|
11356193 |
2001 |
|
Liver Cirrhosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
In this cohort, 35 patients (18.7%) were HCV core antigen (Ag)-positive, and 13 of them (37.1%) died (due to liver cirrhosis (4 cases), hepatocellular carcinoma (1 case), fibrosing cholestatic hepatitis due to HCV (1 case), and infections complicated with chronic hepatitis (6 cases)).
|
28357506 |
2017 |
|
Liver neoplasms
|
0.010 |
GeneticVariation
|
group |
BEFREE |
The 15-patient cohort (17 cases from 2015 to 2018) included those diagnosed with liver tumors (14 hepatocellular carcinoma, 1 cholangiocarcinoma, 1 renal-cell carcinoma, and 1 metastatic colorectal carcinoma) and chosen for radioembolization via a multimodal approach.
|
31155499 |
2019 |