RGS5, regulator of G protein signaling 5, 8490

N. diseases: 52; N. variants: 5
Disease: Parathyroid Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030521
Disease: Parathyroid Neoplasms
Parathyroid Neoplasms 		0.020 AlteredExpression group BEFREE To gain a better understanding of the potential role of RGS5 overexpression in parathyroid neoplasia and PHPT and to investigate whether inhibition of CASR signaling can lead to parathyroid neoplasia, we created and characterized a transgenic mouse strain overexpressing RGS5 specifically in the parathyroid gland. 30690792 2019
CUI: C0030521
Disease: Parathyroid Neoplasms
Parathyroid Neoplasms 		0.020 AlteredExpression group BEFREE Regulator of G protein signaling 5 is highly expressed in parathyroid tumors and inhibits signaling by the calcium-sensing receptor. 21393447 2011