|
Osteosarcoma
|
0.320 |
Biomarker
|
disease |
BEFREE |
BCOR-CCNB3 sarcoma is typically a primary bone sarcoma affecting male adolescents, and this is the first report of it presenting in a kidney of a young child as a CCSK.
|
28833375 |
2018 |
|
Osteosarcoma
|
0.320 |
GeneticVariation
|
disease |
BEFREE |
BCOR-CCNB3 fusion transcripts resulting from an X-chromosomal paracentric inversion were recently identified in a series of unclassifiable soft tissue and bone sarcomas with Ewing sarcoma-like morphology.
|
24805859 |
2014 |
|
Osteosarcoma
|
0.320 |
Biomarker
|
disease |
CTD_human |
A new subtype of bone sarcoma defined by BCOR-CCNB3 gene fusion.
|
22387997 |
2012 |
|
Colorectal Carcinoma
|
0.300 |
GeneticVariation
|
disease |
UNIPROT |
|
|
|
|
Sarcoma
|
0.100 |
Biomarker
|
group |
BEFREE |
BCOR-CCNB3 sarcomas showed swirling fascicular growth.
|
31647130 |
2020 |
|
Sarcoma
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Fine-Needle Aspiration Features of BCOR-CCNB3 Sarcoma.
|
31679010 |
2020 |
|
Malignant neoplasm of soft tissue
|
0.100 |
Biomarker
|
group |
BEFREE |
BCOR-CCNB3 sarcomas showed swirling fascicular growth.
|
31647130 |
2020 |
|
Malignant neoplasm of soft tissue
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Fine-Needle Aspiration Features of BCOR-CCNB3 Sarcoma.
|
31679010 |
2020 |
|
Sarcoma
|
0.100 |
Biomarker
|
group |
BEFREE |
BCOR-CCNB3 fusion sarcoma is cyclin B3-positive, usually occurs in bone or soft tissue of children, and may mimic a poorly differentiated synovial sarcoma.
|
30633925 |
2019 |
|
Sarcoma
|
0.100 |
Biomarker
|
group |
BEFREE |
We also describe the first adult case of MGA-NUTM1 fusion sarcoma, as well as cartilaginous differentiation in a BCOR-CCNB3 fusion sarcoma, which has not been previously reported.
|
31033080 |
2019 |
|
Sarcoma
|
0.100 |
Biomarker
|
group |
BEFREE |
Six of the eight BCOR-CCNB3 positive sarcoma patients were male.
|
30064235 |
2019 |
|
Sarcoma
|
0.100 |
Biomarker
|
group |
BEFREE |
More than 50% of cases stained positive for SATB2 and Pax8, raising the hypothesis of a potential use of these markers in the identification of BCOR-CCNB3 positive undifferentiated/unclassified sarcomas.
|
28420319 |
2019 |
|
Malignant neoplasm of soft tissue
|
0.100 |
Biomarker
|
group |
BEFREE |
BCOR-CCNB3 fusion sarcoma is cyclin B3-positive, usually occurs in bone or soft tissue of children, and may mimic a poorly differentiated synovial sarcoma.
|
30633925 |
2019 |
|
Malignant neoplasm of soft tissue
|
0.100 |
Biomarker
|
group |
BEFREE |
More than 50% of cases stained positive for SATB2 and Pax8, raising the hypothesis of a potential use of these markers in the identification of BCOR-CCNB3 positive undifferentiated/unclassified sarcomas.
|
28420319 |
2019 |
|
Malignant neoplasm of soft tissue
|
0.100 |
Biomarker
|
group |
BEFREE |
We also describe the first adult case of MGA-NUTM1 fusion sarcoma, as well as cartilaginous differentiation in a BCOR-CCNB3 fusion sarcoma, which has not been previously reported.
|
31033080 |
2019 |
|
Malignant neoplasm of soft tissue
|
0.100 |
Biomarker
|
group |
BEFREE |
Six of the eight BCOR-CCNB3 positive sarcoma patients were male.
|
30064235 |
2019 |
|
Sarcoma
|
0.100 |
Biomarker
|
group |
BEFREE |
The DN case was a BCOR-CCNB3 fusion sarcoma.
|
28833375 |
2018 |
|
Malignant neoplasm of soft tissue
|
0.100 |
Biomarker
|
group |
BEFREE |
The DN case was a BCOR-CCNB3 fusion sarcoma.
|
28833375 |
2018 |
|
Sarcoma
|
0.100 |
GeneticVariation
|
group |
BEFREE |
These results are in keeping with a "BCOR-alteration family" of renal and extrarenal neoplasms which includes CCSK and undifferentiated round cell sarcomas of soft tissue/primitive myxoid mesenchymal tumor of infancy (which typically harbor BCOR internal tandem duplication), and BCOR-CCNB3 sarcomas, all of which are primarily driven by BCOR overexpression and have overlapping (but not identical) clinicopathologic features.
|
28817404 |
2017 |
|
Sarcoma
|
0.100 |
Biomarker
|
group |
BEFREE |
A new group of sarcomas with a recurrent BCOR-CCNB3 gene fusion has been recently identified in previously unclassifiable small round cell sarcomas.
|
28756981 |
2017 |
|
Sarcoma
|
0.100 |
Biomarker
|
group |
BEFREE |
Heterogeneous elements included a myxoid spindle cell component in three BCOR-CCNB3 sarcomas and an epithelioid cell component in two CIC-associated sarcomas (one CIC-DUX4-positive and one CIC-DUX4-negative sarcomas).
|
28197724 |
2017 |
|
Malignant neoplasm of soft tissue
|
0.100 |
GeneticVariation
|
group |
BEFREE |
These results are in keeping with a "BCOR-alteration family" of renal and extrarenal neoplasms which includes CCSK and undifferentiated round cell sarcomas of soft tissue/primitive myxoid mesenchymal tumor of infancy (which typically harbor BCOR internal tandem duplication), and BCOR-CCNB3 sarcomas, all of which are primarily driven by BCOR overexpression and have overlapping (but not identical) clinicopathologic features.
|
28817404 |
2017 |
|
Malignant neoplasm of soft tissue
|
0.100 |
Biomarker
|
group |
BEFREE |
A new group of sarcomas with a recurrent BCOR-CCNB3 gene fusion has been recently identified in previously unclassifiable small round cell sarcomas.
|
28756981 |
2017 |
|
Malignant neoplasm of soft tissue
|
0.100 |
Biomarker
|
group |
BEFREE |
Heterogeneous elements included a myxoid spindle cell component in three BCOR-CCNB3 sarcomas and an epithelioid cell component in two CIC-associated sarcomas (one CIC-DUX4-positive and one CIC-DUX4-negative sarcomas).
|
28197724 |
2017 |
|
Sarcoma
|
0.100 |
Biomarker
|
group |
BEFREE |
Nonetheless, NKX2-2 may be helpful to distinguish Ewing sarcoma from some histologic mimics including CIC-DUX4 and BCOR-CCNB3 sarcomas.
|
26847175 |
2016 |