Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0280474
Disease: Childhood Glioblastoma
Childhood Glioblastoma
0.040 Biomarker disease BEFREE LGR5 promotes tumorigenicity and invasion of glioblastoma stem-like cells and is a potential therapeutic target for a subset of glioblastoma patients. 30357839 2019
CUI: C0280474
Disease: Childhood Glioblastoma
Childhood Glioblastoma
0.040 Biomarker disease BEFREE We speculate that the SOX9-LGR5 pathway could be a potentially promising target for the therapy of glioblastoma. 25770425 2015
CUI: C0280474
Disease: Childhood Glioblastoma
Childhood Glioblastoma
0.040 Biomarker disease BEFREE Co-immunofluorescence staining demonstrated the co-localization of CD133- and LGR5-positive cells in glioblastoma tissue sections. 22805276 2013
CUI: C0280474
Disease: Childhood Glioblastoma
Childhood Glioblastoma
0.040 AlteredExpression disease BEFREE Therefore, LGR5 expression may be functionally correlated with the neurogenic competence, and be regulated by OLIG2 in GSCs. 23793848 2013