Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.040 Biomarker disease BEFREE The miR-340-5p/LGR5 axis may provide a new perspective for treatment for breast cancer. 30300682 2019
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.040 AlteredExpression disease BEFREE The human leucine-rich, repeat-containing G protein-coupled receptor 5 (LGR5) is a stem cell marker in numerous adult tissues and is overexpressed in a large number of human carcinoma including colon cancer, breast cancer and oral squamous cell carcinomas (OSCC). 30770730 2019
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.040 Biomarker disease BEFREE Therefore, the purpose of this study was to investigate the clinical significance of the LGR5-β-catenin axis in breast cancer. 29471794 2018
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.040 Biomarker disease BEFREE These findings indicate that LGR5 not only participates in carcinogenesis but also maintained stemness by activating Wnt/β-catenin signaling in breast cancer. 26086949 2015