CDC14A, cell division cycle 14A, 8556

N. diseases: 26; N. variants: 8
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1837608
Disease: DEAFNESS, AUTOSOMAL RECESSIVE 32
DEAFNESS, AUTOSOMAL RECESSIVE 32 		0.700 Biomarker disease GENOMICS_ENGLAND Mutations in CDC14A, Encoding a Protein Phosphatase Involved in Hair Cell Ciliogenesis, Cause Autosomal-Recessive Severe to Profound Deafness. 27259055 2016
CUI: C1837608
Disease: DEAFNESS, AUTOSOMAL RECESSIVE 32
DEAFNESS, AUTOSOMAL RECESSIVE 32 		0.700 Biomarker disease CTD_human Mutations in CDC14A, Encoding a Protein Phosphatase Involved in Hair Cell Ciliogenesis, Cause Autosomal-Recessive Severe to Profound Deafness. 27259055 2016
CUI: C1837608
Disease: DEAFNESS, AUTOSOMAL RECESSIVE 32
DEAFNESS, AUTOSOMAL RECESSIVE 32 		0.700 CausalMutation disease CLINVAR Mutations in CDC14A, Encoding a Protein Phosphatase Involved in Hair Cell Ciliogenesis, Cause Autosomal-Recessive Severe to Profound Deafness. 27259055 2016
CUI: C1837608
Disease: DEAFNESS, AUTOSOMAL RECESSIVE 32
DEAFNESS, AUTOSOMAL RECESSIVE 32 		0.700 GeneticVariation disease UNIPROT Mutations in CDC14A, Encoding a Protein Phosphatase Involved in Hair Cell Ciliogenesis, Cause Autosomal-Recessive Severe to Profound Deafness. 27259055 2016
CUI: C3711374
Disease: Nonsyndromic Deafness
Nonsyndromic Deafness 		0.320 GeneticVariation disease BEFREE Mutations of ESRRB encoding estrogen-related receptor beta cause autosomal-recessive nonsyndromic hearing impairment DFNB35. 18179891 2008
CUI: C0026946
Disease: Mycoses
Mycoses 		0.010 Biomarker group BEFREE Taken together, these results not only reveal the importance of the CDC14 phosphatase in the regulation of development, aflatoxin biosynthesis and virulence in <i>A. flavus</i>, but may also provide a potential target for controlling crop infections of this fungal pathogen. 29868497 2018
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.010 GeneticVariation disease BEFREE The CDC14A and MTMR3 mutations detected in the GC and CRC were deletion or duplication mutations of one base in the nucleotide repeats that would result in premature stops of the amino acid syntheses. 20477815 2010
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.310 GeneticVariation disease BEFREE The CDC14A and MTMR3 mutations detected in the GC and CRC were deletion or duplication mutations of one base in the nucleotide repeats that would result in premature stops of the amino acid syntheses. 20477815 2010
CUI: C1384666
Disease: hearing impairment
hearing impairment 		0.110 GeneticVariation phenotype BEFREE Two families with recessive ESRRB mutations and DFNB35 hearing impairment showed more extensive dental destruction by caries. 25023176 2014
CUI: C0011334
Disease: Dental caries
Dental caries 		0.010 GeneticVariation disease BEFREE Two families with recessive ESRRB mutations and DFNB35 hearing impairment showed more extensive dental destruction by caries. 25023176 2014
CUI: C0333519
Disease: Caries (morphologic abnormality)
Caries (morphologic abnormality) 		0.010 GeneticVariation disease BEFREE Two families with recessive ESRRB mutations and DFNB35 hearing impairment showed more extensive dental destruction by caries. 25023176 2014
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.020 GeneticVariation group BEFREE We also identified a molecular signature for the presence of immunoglobulin variable heavy chain somatic mutation, which includes a number of genes potentially relevant in cancer (CDC14A, ras, and others). 14678979 2003
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.020 GeneticVariation group BEFREE We also identified a molecular signature for the presence of immunoglobulin variable heavy chain somatic mutation, which includes a number of genes potentially relevant in cancer (CDC14A, ras, and others). 14678979 2003
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.020 GeneticVariation group BEFREE We found CDC14A and MTMR3 mutations in five and one cancer (s), respectively. 20477815 2010
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.020 GeneticVariation group BEFREE We found CDC14A and MTMR3 mutations in five and one cancer (s), respectively. 20477815 2010