PDLIM4, PDZ and LIM domain 4, 8572

N. diseases: 44; N. variants: 5
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.040 PosttranslationalModification disease BEFREE Tumor suppressor genes retinoic acid receptor beta (RARbeta) and PDLIM4 are hypermethylated and silenced in prostate cancer (PCa) tissues and PCa cell lines compared to normal prostate cells. 19623543 2009
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.040 AlteredExpression disease BEFREE The re-expression of PDLIM4 in prostate cancer cells has significantly reduced the cell growth and clonogenicity with G1 phase of cell-cycle arrest. 19212833 2009
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.040 Biomarker disease BEFREE Androgen induction of the androgen receptor coactivator four and a half LIM domain protein-2: evidence for a role for serum response factor in prostate cancer. 17975004 2007
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.040 Biomarker disease BEFREE PDLIM4 repression by hypermethylation as a potential biomarker for prostate cancer. 16489065 2006