TP63, tumor protein p63, 8626

N. diseases: 816; N. variants: 64
Disease: Neoplasm Metastasis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.400 Biomarker phenotype BEFREE Furthermore, we determined that tumor metastasis is dependent on MAPK activation in TP63 knockdown HNSCCs. 30910837 2019
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.400 AlteredExpression phenotype BEFREE However, high p63 expression revealed a significant correlation with age (p=0.035), tumor type (p=0.004), American Joint Committee on Cancer stage (p=0.046), lymph node metastasis (p=0.006), lymphovascular invasion (p=0.006), distant metastasis (p=0.049), high Ki67 expression (p=0.000) and K-ras expression (p=0.002). 31056618 2019
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.400 Biomarker phenotype BEFREE In the later stages of progression, HNSCC with and without nodal metastases showed some clear differences including high copy number gains of CCND1, hsa-miR-548k and TP63 in the metastases group. 31427592 2019