TP63, tumor protein p63, 8626

N. diseases: 816; N. variants: 64
Disease: ovarian neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.350 GeneticVariation disease BEFREE We genotyped the p63 (rs873330 [Genbank, refSNP ID] T > C [T: original base, C: mutant base]) and p73 (rs4648551 G > A and rs6695978 G > A) SNPs in ovarian cancers and healthy controls and analyzed the distributions of genotype frequencies to evaluate the association of the genotypes with the risk of ovarian cancer and the clinicopathological characteristics. 23095717 2012
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.350 Biomarker disease CTD_human DeltaNp63alpha confers tumor cell resistance to cisplatin through the AKT1 transcriptional regulation. 21266360 2011
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.350 AlteredExpression disease LHGDN DeltaNp63 expression is associated with poor survival in ovarian cancer. 17998283 2008
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.350 AlteredExpression disease BEFREE Expression of p63 protein is apparently cell lineage specific and in ovarian neoplasms is confined to benign and borderline Brenner tumours. 17880529 2007
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.350 AlteredExpression disease LHGDN Expression of p63 protein is apparently cell lineage specific and in ovarian neoplasms is confined to benign and borderline Brenner tumours. 17880529 2007
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.350 Biomarker disease BEFREE The p63 may be involved in the development of benign and malignant epithelial ovarian tumors. 16445626 2006
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.350 GeneticVariation disease BEFREE These results indicated that p51 gene expression was silent in normal ovarian tissues and primary ovarian cancers, and that mutation of the p51 gene does not play a major role in the development of ovarian cancer. 11179485 2001