RUNX3, RUNX family transcription factor 3, 864

N. diseases: 281; N. variants: 16
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.360 Biomarker group BEFREE The role of miR-301a/Runx3 in lung tumor was evaluated on cell growth, migration and invasion. 31122259 2019
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.360 Biomarker group CTD_human Varied pathways of stage IA lung adenocarcinomas discovered by integrated gene expression analysis. 21552421 2011
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.360 PosttranslationalModification group LHGDN Promoter hypermethylation of RASSF1A and RUNX3 genes as an independent prognostic prediction marker in surgically resected non-small cell lung cancers. 17606310 2007
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.360 PosttranslationalModification group LHGDN Epigenetic inactivation of the RUNX3 gene in lung cancer. 16328045 2006
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.360 PosttranslationalModification group BEFREE Cadherin-13, estrogen receptor-alpha, progesterone receptor, and runt-related transcription factor-3 were frequently methylated in mouse lung tumor-derived cell lines, whereas cadherin-1 and suppressor of cytokine signaling-1 were not. 16603640 2006
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.360 AlteredExpression group LHGDN Frequent hemizygous deletion at 1p36 and hypermethylation downregulate RUNX3 expression in human lung cancer cell lines. 16142337 2005
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.360 PosttranslationalModification group LHGDN Transcriptional silencing of the RUNX3 gene by CpG hypermethylation is associated with lung cancer. 14715269 2004