RUNX3, RUNX family transcription factor 3, 864

N. diseases: 281; N. variants: 16
Disease: Glioblastoma Multiforme ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.340 Biomarker disease BEFREE In conclusion, miR-148-3p directly repressed the expression of DNMT1 and inhibited proliferation, migration, and invasion by regulating DNMT1-RUNX3 axis and the epithelial-mesenchymal transition in GBM. 30982493 2019
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.340 Biomarker disease BEFREE We analyzed epigenetic regulation involvement of two genes related with apoptosis: TIMP3 and RUNX3 in order to define a clinical profile and compare with the most studied gene in GBM: MGMT. 25467143 2014
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.340 Biomarker disease BEFREE RUNX3 has an important role in glioblastoma (GBM) tumorigenesis because of its promoter hypermethylation. 23934435 2014
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.340 PosttranslationalModification disease BEFREE Downregulation of RUNX3 and TES by hypermethylation in glioblastoma. 16909125 2007
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.340 Biomarker disease CTD_human Downregulation of RUNX3 and TES by hypermethylation in glioblastoma. 16909125 2007