Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver
0.070 GeneticVariation disease BEFREE Further, the miRNA-target gene network analysis displayed that the deleted in liver cancer (DLC-1) gene, an important negative regulator for cell motility, was potentially targeted by several differentially expressed miRNAs in HBc-introduced cells. 28982593 2018
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver
0.070 Biomarker disease BEFREE The SH2 domain in tensin family member c-ten requires R474 to bind a RhoGAP called DLC-1 (deleted in liver cancer). 19826001 2009
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver
0.070 GeneticVariation disease BEFREE The deleted in liver cancer (DLC-1) gene at chromosome 8p21-22 is altered mainly by genomic deletion or aberrant promoter methylation in a large number of human cancers such as breast, liver, colon and prostate and is known to have an inhibitory effect on breast and liver tumor cell growth. 14661059 2004
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver
0.070 Biomarker disease BEFREE The DLC-1 gene encoding a regulator of the Rho family of small GTPases is altered in breast, prostate, colon, and liver cancer and has several characteristics of a tumor suppressor gene. 12792785 2003
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver
0.070 Biomarker disease BEFREE DLC-1 (deleted in liver cancer) gene is frequently deleted in hepatocellular carcinoma. 12813468 2003
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver
0.070 GeneticVariation disease BEFREE We investigated the expression and deletion of DLC-1 (frequently deleted in liver cancer gene), first reported in 1998 and having a high homology with rat p122RhoGAP in hepatocellular carcinoma (HCC). 11118037 2000
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver
0.070 Biomarker disease BEFREE DLC-1 may be a tumor suppressor gene in liver cancer as well as in other cancers. 9605766 1998