Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.020 Biomarker group BEFREE These data revealed that the combination of α-mangostin and TRAIL may have a considerable potential for the treatment of oral cancer. 29039600 2017
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.020 Biomarker group BEFREE We examined the TRAIL-mediated cytotoxicity rates of clonally-related primary and metastatic oral cancer (OC) cells and correlated them with the expression levels of TRAIL receptors, cathepsin B and cystatins A, B, C and M. Two pairs of primary (686Tu and 101A) and metastatic (686Ln and 101B) OC cell lines were treated with various concentrations (5 to 1000 ng/ml) of recombinant human TRAIL protein for 14 h, and cell viability and apoptotic rate were determined. 15586230 2005