TNFSF10, TNF superfamily member 10, 8743

N. diseases: 445; N. variants: 10
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.040 Biomarker disease BEFREE Bufalin sensitizes human bladder carcinoma cells to TRAIL-mediated apoptosis. 28693242 2017
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.040 Biomarker disease BEFREE We constructed Arg-Gly-Asp (RGD)-modified oncolytic adenovirus, carrying EGFP or TNF-related apoptosis-inducing ligand (TRAIL) gene (Onco(Ad).RGD-hTERT-EGFP/TRAIL), and applied them to CAR-negative bladder cancer T24 cells and cancer-initiating T24 sphere cells. 25973680 2015
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.040 Biomarker disease BEFREE These results suggest the potential of combining Compound A with TRAIL as an alternative therapy for bladder cancer. 20734142 2011
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.040 Biomarker disease BEFREE Experimental design: A panel of seven bladder cancer cell lines were evaluated for sensitivity to the Smac mimetic compound-A alone, TRAIL alone, chemotherapy alone, compound-A plus TRAIL, and compound-A plus chemotherapy by DNA fragmentation analysis. 20814238 2010