TNFRSF14, TNF receptor superfamily member 14, 8764

N. diseases: 100; N. variants: 3
Disease: Lymphoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024299
Disease: Lymphoma
Lymphoma 		0.030 Biomarker group BEFREE The tumor necrosis factor receptor superfamily member HVEM is one of the most frequently mutated surface proteins in germinal center (GC)-derived B cell lymphomas. 31204070 2019
CUI: C0024299
Disease: Lymphoma
Lymphoma 		0.030 Biomarker group BEFREE HVEM-deficient lymphoma B cells also induce a tumor-supportive microenvironment marked by exacerbated lymphoid stroma activation and increased recruitment of T follicular helper (T<sub>FH</sub>) cells. 27693350 2016
CUI: C0024299
Disease: Lymphoma
Lymphoma 		0.030 Biomarker group BEFREE The increased immune-stimulatory capacity of lymphoma B cells with TNFRSF14 aberrations had clinical relevance, associating with higher incidence of acute GVHD in patients undergoing AHSCT. 27103745 2016