NRP2, neuropilin 2, 8828

N. diseases: 144; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		0.330 Biomarker disease BEFREE Further studies of mouse KO models of ASD genes such as Sema 3F or NRP2 may be informative to clinical phenotypes contributing to the pathogenesis in autism and epilepsy patients. 30635860 2019
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		0.330 GeneticVariation disease BEFREE The NRP2 G allele conferred a 2.29-fold increased risk to autism relative to the T allele (OR = 2.29, 95%CI = 1.23-4.29, P = 0.009). 28484884 2017
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		0.330 GeneticVariation disease LHGDN We found significant genetic association between autism and two of the SNPs of the NRP2 gene (rs849578: P = 0.017, rs849563: P = 0.027), as well as specific haplotypes, especially those formed by rs849563. 17427189 2007
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		0.330 GeneticVariation disease BEFREE We found significant genetic association between autism and two of the SNPs of the NRP2 gene (rs849578: P = 0.017, rs849563: P = 0.027), as well as specific haplotypes, especially those formed by rs849563. 17427189 2007
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		0.330 Biomarker disease CTD_human We found significant genetic association between autism and two of the SNPs of the NRP2 gene (rs849578: P = 0.017, rs849563: P = 0.027), as well as specific haplotypes, especially those formed by rs849563. 17427189 2007
CUI: C0022333
Disease: Jacksonian Seizure
Jacksonian Seizure 		0.300 Biomarker disease CTD_human Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: implications for autism and epilepsy. 18657176 2009
CUI: C0036572
Disease: Seizures
Seizures 		0.300 Biomarker phenotype CTD_human NPN2 deficient mice had shorter seizure latencies, increased vulnerability to seizure-related death, were more likely to develop spontaneous recurrent seizure activity after chemical challenge, and had an increased slope on input/output curves. 18657176 2009
CUI: C0149958
Disease: Complex partial seizures
Complex partial seizures 		0.300 Biomarker disease CTD_human Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: implications for autism and epilepsy. 18657176 2009
CUI: C0234533
Disease: Generalized seizures
Generalized seizures 		0.300 Biomarker disease CTD_human Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: implications for autism and epilepsy. 18657176 2009
CUI: C0234535
Disease: Clonic Seizures
Clonic Seizures 		0.300 Biomarker disease CTD_human Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: implications for autism and epilepsy. 18657176 2009
CUI: C0270824
Disease: Visual seizure
Visual seizure 		0.300 Biomarker disease CTD_human Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: implications for autism and epilepsy. 18657176 2009
CUI: C0270844
Disease: Tonic Seizures
Tonic Seizures 		0.300 Biomarker phenotype CTD_human Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: implications for autism and epilepsy. 18657176 2009
CUI: C0270846
Disease: Epileptic drop attack
Epileptic drop attack 		0.300 Biomarker disease CTD_human Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: implications for autism and epilepsy. 18657176 2009
CUI: C0422850
Disease: Seizures, Somatosensory
Seizures, Somatosensory 		0.300 Biomarker phenotype CTD_human Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: implications for autism and epilepsy. 18657176 2009
CUI: C0422852
Disease: Seizures, Auditory
Seizures, Auditory 		0.300 Biomarker phenotype CTD_human Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: implications for autism and epilepsy. 18657176 2009
CUI: C0422853
Disease: Olfactory seizure
Olfactory seizure 		0.300 Biomarker phenotype CTD_human Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: implications for autism and epilepsy. 18657176 2009
CUI: C0422854
Disease: Gustatory seizure
Gustatory seizure 		0.300 Biomarker phenotype CTD_human Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: implications for autism and epilepsy. 18657176 2009
CUI: C0422855
Disease: Vertiginous seizure
Vertiginous seizure 		0.300 Biomarker phenotype CTD_human Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: implications for autism and epilepsy. 18657176 2009
CUI: C0494475
Disease: Tonic - clonic seizures
Tonic - clonic seizures 		0.300 Biomarker disease CTD_human Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: implications for autism and epilepsy. 18657176 2009
CUI: C0751056
Disease: Non-epileptic convulsion
Non-epileptic convulsion 		0.300 Biomarker phenotype CTD_human Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: implications for autism and epilepsy. 18657176 2009
CUI: C0751110
Disease: Single Seizure
Single Seizure 		0.300 Biomarker disease CTD_human Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: implications for autism and epilepsy. 18657176 2009
CUI: C0751123
Disease: Atonic Absence Seizures
Atonic Absence Seizures 		0.300 Biomarker phenotype CTD_human Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: implications for autism and epilepsy. 18657176 2009
CUI: C0751494
Disease: Convulsive Seizures
Convulsive Seizures 		0.300 Biomarker phenotype CTD_human Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: implications for autism and epilepsy. 18657176 2009
CUI: C0751495
Disease: Seizures, Focal
Seizures, Focal 		0.300 Biomarker phenotype CTD_human Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: implications for autism and epilepsy. 18657176 2009
CUI: C0751496
Disease: Seizures, Sensory
Seizures, Sensory 		0.300 Biomarker phenotype CTD_human Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: implications for autism and epilepsy. 18657176 2009