NRP1, neuropilin 1, 8829

N. diseases: 246; N. variants: 13
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0039685
Disease: Tetralogy of Fallot
Tetralogy of Fallot
0.130 GeneticVariation disease BEFREE Our data provide further evidence of the association between NRP1 polymorphisms and TOF risk, and suggest that rs2228638 may be an excellent marker for TOF risk in European and Chinese Han populations. 29432830 2018
CUI: C0039685
Disease: Tetralogy of Fallot
Tetralogy of Fallot
0.130 AlteredExpression disease BEFREE These findings support that diminished levels of NRP1 contribute to the development of TOF, likely through its function in mediating VEGF signal and vasculogenesis. 29363855 2018
CUI: C0039685
Disease: Tetralogy of Fallot
Tetralogy of Fallot
0.130 GeneticVariation disease BEFREE We found that rs2228638 in NRP1 on 10p11 was significantly increased the risk of TOF (OR = 1.52, 95% CI = 1.13-2.04, P = 0.006), but not in other subgroups including ASD and VSD. 24594544 2014
CUI: C0039685
Disease: Tetralogy of Fallot
Tetralogy of Fallot
0.130 GeneticVariation disease GWASDB Genome-wide association study identifies loci on 12q24 and 13q32 associated with tetralogy of Fallot. 23297363 2013
CUI: C0039685
Disease: Tetralogy of Fallot
Tetralogy of Fallot
0.130 GeneticVariation disease GWASCAT Genome-wide association study identifies loci on 12q24 and 13q32 associated with tetralogy of Fallot. 23297363 2013