PER3, period circadian regulator 3, 8863

N. diseases: 122; N. variants: 19
Disease: Seasonal Affective Disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0085159
Disease: Seasonal Affective Disorder
Seasonal Affective Disorder 		0.320 GeneticVariation disease BEFREE Polymorphisms in a circadian clock-related gene, PER3, are associated with behavioral phenotypes (extreme diurnal preference in arousal and activity) and sleep/mood disorders, including seasonal affective disorder (SAD). 28860482 2017
CUI: C0085159
Disease: Seasonal Affective Disorder
Seasonal Affective Disorder 		0.320 Biomarker disease PSYGENET Such connections to circadian genes such as CLOCK, ARNTL1, NPAS2, PER3 and NR1D1 have been repeatedly demonstrated for bipolar disorders, and to a lesser extent for recurrent depressive disorders and seasonal affective disorders. 21835597 2011
CUI: C0085159
Disease: Seasonal Affective Disorder
Seasonal Affective Disorder 		0.320 GeneticVariation disease BEFREE Certain allelic combinations of NPAS2, PER3, and BMAL1 appear to contribute to the risk of SAD. 17969870 2007
CUI: C0085159
Disease: Seasonal Affective Disorder
Seasonal Affective Disorder 		0.320 Biomarker disease PSYGENET Certain allelic combinations of NPAS2, PER3, and BMAL1 appear to contribute to the risk of SAD. 17969870 2007