ZPR1, ZPR1 zinc finger, 8882

N. diseases: 64; N. variants: 35
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.140 GeneticVariation disease BEFREE There is an association between a genetic polymorphism in the ZNF259 gene involved in lipid metabolism and coronary artery disease. 30902787 2019
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.140 GeneticVariation disease BEFREE Impact of gender and age on the association of the BUD13-ZNF259 rs964184 polymorphism with coronary heart disease. 29339699 2018
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.140 GeneticVariation disease GWASCAT Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases. 27790247 2016
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.140 GeneticVariation disease BEFREE This study highlights the genotypes, genotype scores and haplotypes of the APOA4-APOA5-ZNF259-BUD13 gene cluster that were associated with TG levels in a Chinese population; however, the genetic variants in this gene cluster did not increase the risk of CHD in the Chinese population. 26397108 2015
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.140 GeneticVariation disease GWASCAT Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. 24262325 2014
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.140 GeneticVariation disease BEFREE MG 18∶2 showed an enrichment (P-value = 0.002) of significant associations with CHD-associated SNPs (P-value = 1.2×10-7 for association with rs964184 in the ZNF259/APOA5 region) and a weak, but positive causal effect (odds ratio = 1.05 per SD increment in MG 18∶2, P-value = 0.05) on CHD, as suggested by Mendelian randomization analysis. 25502724 2014
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.140 GeneticVariation disease GWASDB Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. 21347282 2011
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.140 GeneticVariation disease GWASCAT Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. 21378990 2011
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.140 GeneticVariation disease GWASDB Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. 21378990 2011