Malignant tumor of colon
|
0.610 |
GeneticVariation
|
disease |
GWASCAT |
Discovery of common and rare genetic risk variants for colorectal cancer.
|
30510241 |
2019 |
Malignant tumor of colon
|
0.610 |
GeneticVariation
|
disease |
GWASCAT |
Association analyses identify 31 new risk loci for colorectal cancer susceptibility.
|
31089142 |
2019 |
Malignant tumor of colon
|
0.610 |
Biomarker
|
disease |
BEFREE |
Furthermore, Bmi-1 and Cyclin D2 were found to be positively regulated by USP22, which may have mediated the tumorigenic effects of USP22 in human colon cancer.
|
31612065 |
2019 |
Malignant tumor of colon
|
0.610 |
GeneticVariation
|
disease |
GWASCAT |
Novel Common Genetic Susceptibility Loci for Colorectal Cancer.
|
29917119 |
2019 |
Malignant tumor of colon
|
0.610 |
GeneticVariation
|
disease |
GWASCAT |
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
|
23266556 |
2013 |
Malignant tumor of colon
|
0.610 |
Biomarker
|
disease |
RGD |
For example, genes involved in inflammation and matrix proteases and a cell cycle regulator gene, cyclin D2, were highly expressed in colon cancers.
|
15059925 |
2004 |
Malignant tumor of colon
|
0.610 |
Biomarker
|
disease |
CTD_human |
For example, genes involved in inflammation and matrix proteases and a cell cycle regulator gene, cyclin D2, were highly expressed in colon cancers.
|
15059925 |
2004 |
MEGALENCEPHALY-POLYMICROGYRIA-POLYDACTYLY-HYDROCEPHALUS SYNDROME 3
|
0.600 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
De novo CCND2 mutations leading to stabilization of cyclin D2 cause megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome.
|
24705253 |
2014 |
MEGALENCEPHALY-POLYMICROGYRIA-POLYDACTYLY-HYDROCEPHALUS SYNDROME 3
|
0.600 |
GeneticVariation
|
disease |
UNIPROT |
De novo CCND2 mutations leading to stabilization of cyclin D2 cause megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome.
|
24705253 |
2014 |
MEGALENCEPHALY-POLYMICROGYRIA-POLYDACTYLY-HYDROCEPHALUS SYNDROME 3
|
0.600 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
De novo CCND2 mutations leading to stabilization of cyclin D2 cause megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome.
|
24705253 |
2014 |
MEGALENCEPHALY-POLYMICROGYRIA-POLYDACTYLY-HYDROCEPHALUS SYNDROME 3
|
0.600 |
CausalMutation
|
disease |
CLINVAR |
De novo CCND2 mutations leading to stabilization of cyclin D2 cause megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome.
|
24705253 |
2014 |
Megalanecephaly Polymicrogyria-Polydactyly Hydrocephalus Syndrome
|
0.500 |
Biomarker
|
disease |
CTD_human |
A Novel CCND2 Mutation in a Previously Reported Case of Megalencephaly and Perisylvian Polymicrogyria with Postaxial Polydactyly and Hydrocephalus.
|
29642246 |
2018 |
Megalanecephaly Polymicrogyria-Polydactyly Hydrocephalus Syndrome
|
0.500 |
GermlineCausalMutation
|
disease |
ORPHANET |
De novo CCND2 mutations leading to stabilization of cyclin D2 cause megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome.
|
24705253 |
2014 |
Megalanecephaly Polymicrogyria-Polydactyly Hydrocephalus Syndrome
|
0.500 |
Biomarker
|
disease |
CTD_human |
De novo CCND2 mutations leading to stabilization of cyclin D2 cause megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome.
|
24705253 |
2014 |
Colorectal Carcinoma
|
0.450 |
GeneticVariation
|
disease |
GWASCAT |
Association analyses identify 31 new risk loci for colorectal cancer susceptibility.
|
31089142 |
2019 |
Colorectal Carcinoma
|
0.450 |
Biomarker
|
disease |
BEFREE |
The JAK2/STAT3/CCND2 Axis promotes colorectal Cancer stem cell persistence and radioresistance.
|
31511084 |
2019 |
Colorectal Carcinoma
|
0.450 |
Biomarker
|
disease |
BEFREE |
Silencing of CCND2 in SW480 and HT29 CRC cell lines leading to reduced cell proliferative and migrative rates, and enhanced apoptotic rate.
|
31729531 |
2019 |
Colorectal Carcinoma
|
0.450 |
Biomarker
|
disease |
CTD_human |
Discovery of common and rare genetic risk variants for colorectal cancer.
|
30510241 |
2019 |
Colorectal Carcinoma
|
0.450 |
GeneticVariation
|
disease |
GWASCAT |
Novel Common Genetic Susceptibility Loci for Colorectal Cancer.
|
29917119 |
2019 |
Colorectal Carcinoma
|
0.450 |
GeneticVariation
|
disease |
GWASCAT |
Discovery of common and rare genetic risk variants for colorectal cancer.
|
30510241 |
2019 |
Colorectal Carcinoma
|
0.450 |
AlteredExpression
|
disease |
BEFREE |
Our results showed that miR-1297 expression was downregulated in clinical CRC specimens, and such downregulation was associated with upregulated levels of CCND2 expression.
|
28933597 |
2017 |
Colorectal Carcinoma
|
0.450 |
GeneticVariation
|
disease |
BEFREE |
We found that rs10795668 in FLJ3802842 and rs4631962 in CCND2 were significantly associated with CRC risk in the Taiwanese population.
|
24968322 |
2014 |
Colorectal Carcinoma
|
0.450 |
GeneticVariation
|
disease |
GWASDB |
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
|
23266556 |
2013 |
Colorectal Carcinoma
|
0.450 |
GeneticVariation
|
disease |
GWASCAT |
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
|
23266556 |
2013 |
Colorectal Carcinoma
|
0.450 |
GeneticVariation
|
disease |
BEFREE |
We evaluated the implication of USP22 and the candidate targets, such as B-cell-specific murine leukemia virus integration site-1 (BMI-1), cellular homolog of avian myelocytomatosis virus oncogene (c-Myc), cyclin D2, inhibitor of cyclin-dependent kinase (CDK) 4 (p16INK4a), and an alternate reading frame product of the CDKN2A locus (p14ARF), in matched samples comprising carcinoma and adjacent non-cancerous mucosa from 82 patients with CRC using quantitative reverse transcription-polymerase chain reaction and immunostaining analyses.
|
21039844 |
2010 |