WNT3A, Wnt family member 3A, 89780

N. diseases: 141; N. variants: 5
Disease: Glioblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.050 Biomarker disease BEFREE In vivo, tumors formed from Wnt3a-stimulated glioblastoma cells presented greater microglial infiltration and more aggressive characteristics such as growth rate than untreated tumors. 29948952 2019
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.050 Biomarker disease BEFREE Meanwhile, the mRNA and protein expression levels of NTSR1 were increased by the Wnt pathway activator Wnt3a and decreased by the Wnt inhibitor iCRT3 in glioblastoma cells. 29065410 2017
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.050 AlteredExpression disease BEFREE We first demonstrated the non-specific interaction of Wnt3a and Wnt5a with the receptors LRP6 and ROR2 and the up-regulation of the Wnt pathway in glioblastoma cells. 25301448 2015
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.050 AlteredExpression disease BEFREE We found that Wnt3a and ABCB1, which encodes for Pgp, were both highly expressed in glioblastoma stem cells and reduced by temozolomide. 23897632 2013
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.050 AlteredExpression disease BEFREE Wnt3a mediated activation of Wnt/β-catenin signaling promotes tumor progression in glioblastoma. 23337036 2013