MIDN, midnolin, 90007

N. diseases: 3; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.020 AlteredExpression disease BEFREE Midnolin is a novel regulator of parkin expression and is associated with Parkinson's Disease. 28724963 2017
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.020 Biomarker disease BEFREE In the present study, we aimed to replicate the genetic association between MIDN and PD in a large British population cohort. 31588691 2019
CUI: C4511452
Disease: Sporadic Parkinson disease
Sporadic Parkinson disease
0.020 AlteredExpression disease BEFREE Taken together, these findings indicate that MIDN regulates the expression of a wide variety of genes, including multiple PD-causative genes and is associated with PD onset. 29311479 2018
CUI: C4511452
Disease: Sporadic Parkinson disease
Sporadic Parkinson disease
0.020 Biomarker disease BEFREE Interestingly, a genetic approach revealed that 10.5% of patients with sporadic Parkinson's disease (PD) had a lower MIDN gene copy number whereas no copy number variation was observed in healthy people, suggesting that MIDN is involved in PD pathogenesis. 28724963 2017
CUI: C3160718
Disease: PARKINSON DISEASE, LATE-ONSET
PARKINSON DISEASE, LATE-ONSET
0.010 GeneticVariation disease BEFREE We recently found that 10.5% of sporadic Parkinson's disease (PD) patients lacked one copy of the midnolin (MIDN) gene. 29311479 2018