Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003431
Disease: Antisocial Personality Disorder
Antisocial Personality Disorder
0.100 GeneticVariation disease BEFREE The men completed the WAI 3 months into their treatment program, while psychopathy was measured via file-based ratings of the Hare's Psychopathy Checklist-Revised (PCL-R), and outcome data were collected via the Canadian Police Information Centre. 29294686 2020
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 Biomarker disease BEFREE Within the TBI group, partial correlations that controlled for age, sex, TSLI, and antianxiety/depression medication use showed that tau concentrations were significantly correlated with greater symptom severity, as measured with the NSI, PCL, and PHQ-9. 31033745 2020
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 GeneticVariation disease BEFREE PTSD Checklist-Civilian Version (PCL-C); Neurobehavioral Symptom Inventory (NSI); Ohio State University TBI Identification Method; Patient Health Questionnaire-9 (PHQ-9); Simoa-measured concentrations of tau, amyloid-beta (Aβ) 40, Aβ42, and neurofilament light (NFL). 31033745 2020
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 GeneticVariation disease BEFREE PTSD and partial PTSD were measured using the PCL-5. 31821960 2020
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 Biomarker disease BEFREE PTSD symptoms were measured by the PTSD Checklist for DSM-5 (PCL-5), and the severity (total symptoms) and symptom clusters were calculated according to the hybrid seven-factor model of DSM-5 PTSD. 31655035 2020
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 Biomarker disease BEFREE Fifty-six patients (71% female, 61% White) with mixed etiology chronic pain completed the PTSD Checklist-Civilian Version (PCL-C) as part of their appointment with a pain psychologist at a tertiary outpatient pain clinic. 31646748 2020
CUI: C0003431
Disease: Antisocial Personality Disorder
Antisocial Personality Disorder
0.100 GeneticVariation disease BEFREE Studies were included if they (1) reported physiological measures of threat response as the primary outcome measure (2) indexed psychopathy using a well-validated clinician rated instrument such as the PCL-R (3) investigated male offenders between 18 and 60 years of age (4) reported threat processing analyses using both Factor 1 and Factor 2 scores (5) provided sufficient data to calculate effect sizes and (6) were published in English-language peer-reviewed journals. 31661520 2019
CUI: C0003431
Disease: Antisocial Personality Disorder
Antisocial Personality Disorder
0.100 GeneticVariation disease BEFREE The modern conception of Psychopathy was introduced by Clerckley in "Mask of Sanity" (1941), and refined by Hare with the construction of the PCL (1980, 1991), a gold standard instrument for the evaluation of the disorder. 31488769 2019
CUI: C0003431
Disease: Antisocial Personality Disorder
Antisocial Personality Disorder
0.100 Biomarker disease BEFREE We examined 62 participants (31 heroin dependent individuals and 31 healthy controls) with the Psychopathy Checklist: Screening version (PCL:SV, Hart et al., 1995) and the Toronto Alexithymia Scale-20 (TAS-20, Bagby et al., 1994). 31649591 2019
CUI: C0003431
Disease: Antisocial Personality Disorder
Antisocial Personality Disorder
0.100 Biomarker disease BEFREE In the current report, psychopathy scores (measured via the Psychopathy Checklist: Youth Version (PCL:YV)) were negatively related to hemodynamic activity within input nuclei of the basal ganglia (i.e., the caudate and nucleus accumbens), as well as intrinsic/output nuclei (i.e., the globus pallidus and substantia nigra) and related nuclei (i.e., the subthalamic nucleus) during error-related processing. 31104203 2019
CUI: C0003431
Disease: Antisocial Personality Disorder
Antisocial Personality Disorder
0.100 GeneticVariation disease BEFREE The aim of the present study is to consider the underlying factor structure of the PCL:SV (Psychopathy Checklist Screening Version) in a Danish sample as well as considering the role of antisocial behavior in the psychopathy construct. 31274196 2019
CUI: C0003431
Disease: Antisocial Personality Disorder
Antisocial Personality Disorder
0.100 Biomarker disease BEFREE Forensic mental health professionals ranked the 20 Psychopathy Checklist-Revised (PCL-R) items on their importance to psychopathy. 30650005 2019
CUI: C0003431
Disease: Antisocial Personality Disorder
Antisocial Personality Disorder
0.100 Biomarker disease BEFREE To build upon this prior research, the current study used data on male offenders from the Incarcerated Serious and Violent Young Offender Study to examine the network structure of the Comprehensive Assessment of Psychopathic Personality - Institutional Rating Scale (CAPP-IRS; n = 224) and Psychopathy Checklist: Youth Version (PCL:YV; n = 445). 30887147 2019
CUI: C0003431
Disease: Antisocial Personality Disorder
Antisocial Personality Disorder
0.100 Biomarker disease BEFREE The Psychopathy Checklist: Screening Version (PCL:SV; Hart, Cox, & Hare, 1995) and Borderline Features scale of the Personality Assessment Inventory (PAI; Morey, 1991) were administered at the outset of incarceration. 30355022 2019
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.100 GeneticVariation group GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE All participants were assessed for PTSD using the Chinese PC-PTSD-5 for children and the PTSD Checklist for DSM-5 (PCL-5), and assessed for anxiety using the Chinese version of the State Anxiety Scale for Children (CSAS-C), and for depression using the Children's Depression Inventory - Short Form (CDI-S). 31158781 2019
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE <b>Method</b>: Three groups of asylum seekers from different countries (<i>N</i> = 99) completed the Traumatic Grief Inventory Self-Report Version (TGI-SR), Posttraumatic Stress Disorder Checklist-5 (PCL-5), and Patient Health Questionnaire depression module (PHQ-9). 30988893 2019
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 Biomarker disease BEFREE PCL-5 scores correlated strongly with scores on measures of depression (ρ = 0.71, <i>p</i> < .001), anxiety (ρ = 0.61, <i>p</i> < .001), and rumination (ρ = 0.68, <i>p</i> < .001), supporting convergent validity. 30774783 2019
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.100 GeneticVariation disease BEFREE In all subjects, the IL-1β levels were correlated with PCL scores, after controlling for covariates, including age, education, marital status and gender, trauma exposure severity and depression. 30711869 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker group BEFREE According to characteristics of the tumor microenvironment, in this study, we aimed to synthesize matrix metalloproteinase (MMP)-responsive curcumin (Cur)-loaded nanoparticles (Cur-P-NPs) based on amphiphilic block copolymer (MePEG-peptide-PET-PCL) with MMP-cleavable peptide (GPLGIAGQ) and penetrating peptide (r9), modified to improve tumor targeting and cellular uptake. 31691601 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker group BEFREE Compared with free Ara-C, PCL-ss-Ara@Sgc8-BSA significantly enhanced tumor growth inhibition in mice bearing CCRF-CEM xenograft tumors, while causing little side effects, and improved the survival rate of CCRF-CEM tumor-bearing mice in vivo. 31769777 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker group BEFREE HA-PCL-CAP-administered groups presented greater therapeutic efficacy as revealed through reduced tumor volume and improved animal survival rate. 30178279 2019
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 GeneticVariation disease BEFREE At 3 months, PTSD will be defined by a ≥ 33 score at PTSD Check List for DSM-5 (PCL-5) through a telephone interview. 31146712 2019
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 GeneticVariation disease BEFREE Study patients were screened for PTSD using the PCL-5 checklist for DSM-5. 30878218 2019
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 GeneticVariation disease BEFREE Sixty-seven patients with PTSD and 72 patients without PTSD were assessed using the PTSD Checklist for DSM-5 (PCL-5) and psychiatric interview. 30579176 2019