PRC1, protein regulator of cytokinesis 1, 9055

N. diseases: 73; N. variants: 8
Disease: Non-Small Cell Lung Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.020 AlteredExpression disease BEFREE The role of BMI1 in the epigenetic activity of PRC1 is particularly relevant in several cancers, particularly Non-Small Cell Lung Cancer (NSCLC). 31323431 2019
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.020 Biomarker disease BEFREE Significantly, we also show that PRC1 is required for tumorigenesis <i>in vivo</i> using a mouse model for non-small cell lung cancer driven by oncogenic K-RAS and loss of p53. 29435157 2018