Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.020 AlteredExpression disease BEFREE Here, we found that ZNF479 regulates MT-1 expression by modulating ASH2L in HCC. 31138789 2019
CUI: C3888194
Disease: MIXED LINEAGE LEUKEMIA
MIXED LINEAGE LEUKEMIA
0.020 Biomarker disease BEFREE ZNF479 induced the expression of DNMT1, UHRF1, and mixed-lineage leukemia (MLL) complex proteins (ASH2L and Menin), and increased tri-methylated histone H3 (H3K4me3) levels, but suppressed H3K4 (H3K4me2) di-methylation. 31138789 2019
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
0.010 AlteredExpression group BEFREE Specific inhibition of DPY30 activity by ASH2L-derived peptides suppresses blood cancer cell growth. 31251903 2019
CUI: C3890429
Disease: Liquid Tumor
Liquid Tumor
0.010 AlteredExpression disease BEFREE Specific inhibition of DPY30 activity by ASH2L-derived peptides suppresses blood cancer cell growth. 31251903 2019
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.020 Biomarker phenotype BEFREE circ-ASH2L play an important role in tumor invasion, and high circ-ASH2L may be a useful marker of PDAC diagnosis or progression. 31718694 2019
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.010 Biomarker phenotype BEFREE Circ-ASH2L served as a miRNA sponge for miR-34a and promoted tumor progression in vivo. 31718694 2019
CUI: C1335302
Disease: Pancreatic Ductal Adenocarcinoma
Pancreatic Ductal Adenocarcinoma
0.010 Biomarker disease BEFREE Circ-ASH2L promotes tumor progression by sponging miR-34a to regulate Notch1 in pancreatic ductal adenocarcinoma. 31718694 2019
ANOPHTHALMIA AND PULMONARY HYPOPLASIA
0.010 Biomarker disease BEFREE circ-ASH2L play an important role in tumor invasion, and high circ-ASH2L may be a useful marker of PDAC diagnosis or progression. 31718694 2019