Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
0.030 Biomarker disease BEFREE Specifically, we address the role of DNA-PKcs and the novel potential end-joining factor KUB3 in maintaining the radioresistant phenotype, the interrelationship between genetic lesions and repair mechanisms, and new perspectives that emerge from the identification of glioblastoma stem cells. 18066094 2007
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
0.030 Biomarker disease BEFREE Northern blot analysis of glioblastoma shows a strong correlation between KUB3 amplification and overexpression. 11571779 2001
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
0.030 AlteredExpression disease BEFREE Furthermore, we found that a siRNA-mediated reduction of the endogenous KUB3 expression in glioblastoma cells resulted in a reduction of the repair efficiency. 23670597 2013
CUI: C0278878
Disease: Adult Glioblastoma
Adult Glioblastoma
0.030 Biomarker disease BEFREE Specifically, we address the role of DNA-PKcs and the novel potential end-joining factor KUB3 in maintaining the radioresistant phenotype, the interrelationship between genetic lesions and repair mechanisms, and new perspectives that emerge from the identification of glioblastoma stem cells. 18066094 2007
CUI: C0278878
Disease: Adult Glioblastoma
Adult Glioblastoma
0.030 Biomarker disease BEFREE Northern blot analysis of glioblastoma shows a strong correlation between KUB3 amplification and overexpression. 11571779 2001
CUI: C0278878
Disease: Adult Glioblastoma
Adult Glioblastoma
0.030 AlteredExpression disease BEFREE Furthermore, we found that a siRNA-mediated reduction of the endogenous KUB3 expression in glioblastoma cells resulted in a reduction of the repair efficiency. 23670597 2013
CUI: C0280474
Disease: Childhood Glioblastoma
Childhood Glioblastoma
0.030 AlteredExpression disease BEFREE Furthermore, we found that a siRNA-mediated reduction of the endogenous KUB3 expression in glioblastoma cells resulted in a reduction of the repair efficiency. 23670597 2013
CUI: C0280474
Disease: Childhood Glioblastoma
Childhood Glioblastoma
0.030 Biomarker disease BEFREE Specifically, we address the role of DNA-PKcs and the novel potential end-joining factor KUB3 in maintaining the radioresistant phenotype, the interrelationship between genetic lesions and repair mechanisms, and new perspectives that emerge from the identification of glioblastoma stem cells. 18066094 2007
CUI: C0280474
Disease: Childhood Glioblastoma
Childhood Glioblastoma
0.030 Biomarker disease BEFREE Northern blot analysis of glioblastoma shows a strong correlation between KUB3 amplification and overexpression. 11571779 2001
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme
0.030 AlteredExpression disease BEFREE Furthermore, we found that a siRNA-mediated reduction of the endogenous KUB3 expression in glioblastoma cells resulted in a reduction of the repair efficiency. 23670597 2013
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme
0.030 Biomarker disease BEFREE Northern blot analysis of glioblastoma shows a strong correlation between KUB3 amplification and overexpression. 11571779 2001
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme
0.030 Biomarker disease BEFREE Specifically, we address the role of DNA-PKcs and the novel potential end-joining factor KUB3 in maintaining the radioresistant phenotype, the interrelationship between genetic lesions and repair mechanisms, and new perspectives that emerge from the identification of glioblastoma stem cells. 18066094 2007
CUI: C0017638
Disease: Glioma
Glioma
0.020 AlteredExpression disease BEFREE The data provide the first evidence for a link between the level of KUB3 amplification and expression in glioma and DSB repair efficiency. 23670597 2013
CUI: C0017638
Disease: Glioma
Glioma
0.020 Biomarker disease BEFREE We determined the amplification frequency of KUB3 in glioma with different grading. 11571779 2001
CUI: C0004114
Disease: Astrocytoma
Astrocytoma
0.010 Biomarker disease BEFREE We analyzed a total of 102 glioma primary tumors and found KUB3 to be amplified in 12/82 (14%) glioblastomas, 4/13 anaplastic astrocytomas (30%), and 2/4 astrocytomas, but in none of three pilocytic astrocytomas. 11571779 2001
CUI: C0334579
Disease: Anaplastic astrocytoma
Anaplastic astrocytoma
0.010 Biomarker disease BEFREE We analyzed a total of 102 glioma primary tumors and found KUB3 to be amplified in 12/82 (14%) glioblastomas, 4/13 anaplastic astrocytomas (30%), and 2/4 astrocytomas, but in none of three pilocytic astrocytomas. 11571779 2001
CUI: C0334583
Disease: Pilocytic Astrocytoma
Pilocytic Astrocytoma
0.010 Biomarker disease BEFREE We analyzed a total of 102 glioma primary tumors and found KUB3 to be amplified in 12/82 (14%) glioblastomas, 4/13 anaplastic astrocytomas (30%), and 2/4 astrocytomas, but in none of three pilocytic astrocytomas. 11571779 2001
CUI: C1261473
Disease: Sarcoma
Sarcoma
0.010 Biomarker group BEFREE Our results also indicate that the increase in sarcoma incidence in Polμ<sup>-/-</sup>P53<sup>-/-</sup> mice could be associated with Cdk4 and Kub3 amplification and overexpression. 28460268 2017
CUI: C4551686
Disease: Malignant neoplasm of soft tissue
Malignant neoplasm of soft tissue
0.010 Biomarker group BEFREE Our results also indicate that the increase in sarcoma incidence in Polμ<sup>-/-</sup>P53<sup>-/-</sup> mice could be associated with Cdk4 and Kub3 amplification and overexpression. 28460268 2017
CUI: C0021704
Disease: Intelligence
Intelligence
0.100 GeneticVariation phenotype GWASCAT A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence. 29326435 2019