IL1RL1, interleukin 1 receptor like 1, 9173

N. diseases: 117; N. variants: 51
Disease: Ulcerative Colitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.030 Biomarker disease BEFREE This review summarizes the role of the IL-33/ST2L axis in the UC and CRC microenvironments. 29329638 2019
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.030 GeneticVariation disease BEFREE Sequencing of a distal IL1RL1 promoter region demonstrated that SNPs rs6543115(C) and rs6543116(A) are associated with increased sST2 in UC patients on corticosteroids. 28860510 2017
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.030 GeneticVariation disease BEFREE Upon genotype-phenotype evaluation, an increased frequency of extensive colitis in adult UC (P = 0.019) and in steroid-responsive pediatric patients (P = 0.024) carrying the IL-33 rs3939286 risk genotype, was observed. mRNA expression of IL-33 and IL1RL1 in inflamed IBD biopsy samples was significantly increased. 23634226 2013