T-Cell Lymphoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our data indicate that LMP1-IgG may provide a novel and promising therapeutic strategy for the treatment of LMP1-positive ENKTL.
|
28009988 |
2017 |
T-Cell Lymphoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
LMP1 promotes nasal NK/T-cell lymphoma cell function by eIF4E via NF-κB pathway.
|
26397141 |
2015 |
T-Cell Lymphoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Downregulation of miR-15a due to LMP1 promotes cell proliferation and predicts poor prognosis in nasal NK/T-cell lymphoma.
|
23963825 |
2014 |
T-Cell Lymphoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Epstein-Barr virus BART9 miRNA modulates LMP1 levels and affects growth rate of nasal NK T cell lymphomas.
|
22102884 |
2011 |
T-Cell Lymphoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Clinical usefulness of serum EBV DNA levels of BamHI W and LMP1 for Nasal NK/T-cell lymphoma.
|
17385697 |
2007 |
T-Cell Lymphoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Although it is still not clear what the most specific and biologic variation of LMP1 gene in nasal NK/T-cell lymphoma is, the sequence data may be valuable on the study for pathogenesis of nasal NK/T-cell lymphoma and EBV molecular epidemiology.
|
16917737 |
2007 |
T-Cell Lymphoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Comparative analysis of NK/T-cell lymphoma and peripheral T-cell lymphoma in Korea: Clinicopathological correlations and analysis of EBV strain type and 30-bp deletion variant LMP1.
|
14629296 |
2003 |
T-Cell Lymphoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Preferential localization of the Epstein-Barr virus (EBV) oncoprotein LMP-1 to nuclei in human T cells: implications for its role in the development of EBV genome-positive T-cell lymphomas.
|
11907247 |
2002 |
T-Cell Lymphoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
All isolates without the LMP-1-Xho-1 site had a 30 bp deletion in the carboxy terminus of the LMP-1 gene, except for the isolate from a patient with angioimmunoblastic lymphadenophathy-like T-cell lymphoma in which a novel Nco-1 site was present in exon 1.
|
11002254 |
2000 |
T-Cell Lymphoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
A deletion within the LMP-1 gene was found in 4 of 25 cases (16%) of EBV-positive T-cell lymphomas, 4 of 10 cases (40%) of EBV-positive HD cases, and 2 of 13 specimens (15%) with amplified PCR products from 49 healthy individuals.
|
11039671 |
2000 |
T-Cell Lymphoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Genetic studies showed that the virus detected in the T-cell lymphoma was indistinguishable, with respect to type and previously defined LMP-1 and EBNA-1 gene variations, from virus detected in the peripheral blood T cells 19 months earlier.
|
9490694 |
1998 |
T-Cell Lymphoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
These results indicate that EBV in Japanese non-Hodgkin's lymphomas is exclusively of type A with a specific deletion in LMP-1 and that it tends to be present in T cell lymphomas.
|
9260592 |
1997 |
T-Cell Lymphoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
The virus shows a type II latency pattern (EBNA1+, LMP1+, EBNA2-) that seems to be similar to the EB virus associated nasal T cell lymphomas in oriental countries.
|
8666691 |
1996 |
T-Cell Lymphoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Forty-two cases of Chinese T-cell lymphoma were studied for expression of Epstein-Barr virus (EBV) encoded RNA (EBER-1) and EBV latent membrane protein-1 (LMP-1) using in situ hybridization and immunohistochemistry, respectively.
|
8181803 |
1994 |
T-Cell Lymphoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Therefore, we have investigated in T-cell lymphomas with similar morphology originating from different sites, ie, nose (n = 5; all pleomorphic small- or medium- and large-cell T-cell lymphomas [PTL]), skin (PTL, n = 6; anaplastic large-cell [ALCL], n = 11), gut (PTL, n = 8; ALCL, n = 4), and lung (PTL, n = 6), the presence of Epstein-Barr virus (EBV) at the DNA, RNA (EBER 1 and EBER 2), and protein level (LMP-1).
|
8123852 |
1994 |
T-Cell Lymphoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Transformation-associated EBV latent membrane protein 1 (LMP 1) was detected in 13 (6%) NHL, comprising 4 (4%) high-grade B-cell, 8 (10%) peripheral T-cell, and 1 non-B-cell, non-T-cell lymphomas.
|
1318639 |
1992 |