Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
The adiponectin receptor agonist AdipoRon normalizes glucose metabolism and prevents obesity but not growth retardation induced by glucocorticoids in young mice.
|
31778708 |
2020 |
Obesity
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Several studies have found that cord blood adiponectin levels are related with postnatal growth trajectories, and it has been suggested that low adiponectin levels in women with pregestational obesity enhance placental insulin sensitivity and activation of placental amino acid transport systems, supporting fetal overgrowth.
|
31654701 |
2020 |
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
ADIPOQ G rs266729 and TNF- 308 A allele are associated with obesity, MetS/NAFLD and insulin resistance.
|
31659105 |
2020 |
Obesity
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Low maternal adiponectin levels in obese mice in late pregnancy are mechanistically linked to in utero programming of cardiac dysfunction in their offspring.
|
31076636 |
2020 |
Obesity
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Low levels of total and HMW adiponectin may predict the development of NAFL independent of pathophysiological factors including obesity and insulin resistance.
|
31765666 |
2020 |
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
A doubling of adiponectin levels was associated with a 30% increased risk of overweight/obesity in boys (RR = 1.30; 95% CI: 1.02, 1.64).
|
31845502 |
2020 |
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
Considering that most scientific knowledge on adiponectin dysregulation in obesity is from the study of adipose tissue, the present review summarizes and discusses the literature available to date regarding the effects of obesity on skeletal muscle adiponectin induction, along with the potential effects of different exercise prescriptions on this response in an obesity context.
|
31706980 |
2020 |
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
After pregnancy, adiponectin increased in both groups, but more markedly in OB where it reached trimester 1 levels.
|
31551485 |
2020 |
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
Adiponectin, a cytokine released by adipose tissue is associated with these disorders and obesity via inflammatory processes.
|
31539673 |
2020 |
Obesity
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
We analyzed associations of these polymorphisms with anthropometric parameters, lipid profile, as well as adiponectin, leptin and soluble leptin receptor (sOB-R) levels in prepubertal healthy children, to search for their possible role in the risk of obesity and obesity-related disorders.
|
31204527 |
2020 |
Obesity
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Obesity is associated to a low-grade inflammation that alters the expression of adiponectin, leptin, IL-6, Monocyte Chemotactic Protein 1 (MCP1), TRAIL, LIGHT/TNFSF14, OPG, and TNFα.
|
31130918 |
2019 |
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Only FTO rs9939609 A>T polymorphism was associated with obesity and no association was observed with ADIPOQ rs2441666 G>T and ACE rs4340288 DIP.
|
30416093 |
2019 |
Obesity
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The aim of this study was to investigate the association between the RANKL and c-Fos gene methylation on obesity with body mass index (BMI), lipid parameters, homeostasis model assessment of insulin resistance (HOMA-IR), plasma leptin, adiponectin and resistin levels.
|
31364017 |
2019 |
Obesity
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Psoriasis in obesity: comparison of serum levels of leptin and adiponectin in obese subjects - cases and controls.
|
31090824 |
2019 |
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
Pulmonary Hypertension and Obesity: Focus on Adiponectin.
|
30791536 |
2019 |
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Leptin/adiponectin imbalance is associated with increased risk of developing obesity and type 2 diabetes mellitus.
|
30841005 |
2019 |
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
In this study, we investigated the effects of HFD on obesity and insulin resistance in two distinct types of adipose-specific L-PGDS gene knockout (KO) mice: fatty acid binding protein 4 (fabp4, aP2)-Cre/L-PGDS <sup>flox/flox</sup> and adiponectin (AdipoQ)-Cre/L-PGDS <sup>flox/flox</sup> mice.
|
30760783 |
2019 |
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
Adiponectin homolog novel osmotin protects obesity/diabetes-induced NAFLD by upregulating AdipoRs/PPARα signaling in ob/ob and db/db transgenic mouse models.
|
30473057 |
2019 |
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
We explored the effects of Roux-en-Y gastric bypass (RYGB) on the circulating levels of adiponectin, leptin, and the adiponectin/leptin (Adpn/Lep) ratio in patients with obesity and type 2 diabetes (T2D).
|
31484347 |
2019 |
Obesity
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
HDL cholesterol and adiponectin levels were higher in the eutrophic group compared to the obese and excess-weight groups (p<0.01).
|
29856943 |
2019 |
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
Adiponectin is an adipokine that improves insulin sensitivity in obesity-related metabolic disorders, including diabetes, but its efficacy is unknown.
|
31048658 |
2019 |
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
The therapeutic potential of adiponectin regulation has received interest because of its association with diverse human disease conditions, such as diabetes, obesity, atherosclerosis, and cancer.
|
30672698 |
2019 |
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology.
|
31178129 |
2019 |
Obesity
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Obesity and diabetes were associated with increased leptin and decreased adiponectin plasma levels, higher protein expression of leptin and IL-6 in SAT, and higher visfatin protein expression in EAT.
|
31533725 |
2019 |
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
Adiponectin and PPAR: a setup for intricate crosstalk between obesity and non-alcoholic fatty liver disease.
|
31656991 |
2019 |