Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.400 AlteredExpression disease BEFREE Moreover, while men with MS exhibited an expected lower adiponectinemia, they displayed 2.1-fold higher adiponectin levels in SP than men without MS. 31705791 2020
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.400 Biomarker disease BEFREE Our study found lower insulin resistance, serum triglyceride, and SBP and higher adiponectin concentrations among patients with metabolic syndrome in highest quartiles of DDS. 31786572 2020
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.400 Biomarker disease BEFREE Restoring normal adiponectin concentrations by infusion in obese pregnant mice prevents placental dysfunction, foetal overgrowth and metabolic syndrome in the offspring. 31076636 2020
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.400 GeneticVariation disease BEFREE In this way, the present study aimed to analyze the possible association between the ADIPOQ + 45T> G gene polymorphism, usual diet and metabolic syndrome in the elderly. 29313754 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.400 AlteredExpression disease BEFREE We aim to determine the serum adiponectin levels in Chinese patients with schizophrenia, and explore the relationship between adiponectin levels and metabolic parameters, including MetS and its components. 31059867 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.400 AlteredExpression disease BEFREE Adiponectin levels were significantly higher in patients with lower BMI (<i>r</i> = -0.23; <i>p</i> < .0001) and in patients without metabolic syndrome compared to patients with higher BMI and with metabolic syndrome. 31179792 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.400 Biomarker disease BEFREE The hormone adiponectin is secreted by white adipocytes and has been put forward as a key mediator of obesity-linked insulin resistance and the metabolic syndrome. 31337827 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.400 Biomarker disease BEFREE The addition of leptin and adiponectin to the regression models did not substantially change the impact of thyroid hormones on components of MS. Our data suggest that, even within the euthyroid range, excess of truncal adipose tissue is associated with variations in FT4. 31151171 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.400 Biomarker disease BEFREE Adiponectin, leptin and hs-CRP were significantly modified in the group with MetS (p=0.04, p=0.04, p=0.01, respectively). 30530892 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.400 Biomarker disease BEFREE ANGPTL8 and adiponectin concentrations were measured in PCOS patients with or without MetS and in their corresponding healthy controls. 31346314 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.400 GeneticVariation disease BEFREE RT-PCR and immunoassy analysis were used to study circulating miRNA profile, adipokines; adiponectin (A), leptin (L), and L/A ratio as well as other factors of metabolic syndrome (MS) in 250 adolescents with severe obesity. 30309709 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.400 AlteredExpression disease BEFREE The adipokines DPP-4 and leptin in the serum can influence the body fat distribution of patients with T2MD; there is an important association of DPP-4, leptin and ADPN levels with MS, which may be used as therapeutic targets for multiple metabolism disorders of T2MD. 29205013 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.400 AlteredExpression disease BEFREE Therefore, the aim of this study is to examine whether the association between serum adiponectin levels and clinical outcomes in non-diabetic CKD patients is independent of adiposity and metabolic syndrome. 31323071 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.400 AlteredExpression disease BEFREE Our results showed that, overall, both CGN and SCGN were more effective in reversing obesity and related metabolic syndromes to normal levels than T. Furthermore, these findings suggested that CGN- and SCGN-modulated gut dysbiosis induced by a high-fat diet, which may play an influencing role in adiponectin dysregulation. 31117266 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.400 Biomarker disease BEFREE Chemerin and adiponectin are adipokines assumed to be involved in the development of metabolic syndrome-related phenotypes like hepatic steatosis. 31265993 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.400 GeneticVariation disease BEFREE Markers of cartilage metabolism (cartilage oligomeric matrix protein [COMP], hyaluronan), metabolic syndrome (adiponectin, adipsin, resistin, hepatocyte growth factor [HGF], insulin, leptin) and inflammation (C-reactive protein [CRP], interleukin-1β [IL-1β], IL-6, IL-8, tumour necrosis factor alpha [TNFα], monocyte chemoattractant protein-1 [MCP-1], nerve growth factor [NGF]) were compared in serum samples from 201 patients with OA, 77 patients with PsA and 76 controls. 30910989 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.400 Biomarker disease BEFREE Even Short-Term Telmisartan Treatment Ameliorated Insulin Resistance But Had No Influence on Serum Adiponectin and Tumor Necrosis Factor-Alpha Levels in Hypertensive Patients with Metabolic Syndrome. 30688550 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.400 Biomarker disease BEFREE Moreover, lower Ad concentrations are associated with the development of metabolic syndrome, insulin resistance and hypertension in pediatric subjects. 31262082 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.400 Biomarker disease BEFREE These results strengthen the idea of adiponectin as a key biological factor that links metabolic syndrome and emotional disorders. 29988086 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.400 Biomarker disease BEFREE The synovium and IPFP in the MetS-OA group secreted more leptin and less adiponectin than those in the non-MetS-OA group (Leptin: 5.32 vs. 1.28 in synovium, respectively; <i>p</i>= 0.028; 6.44 vs. 0.88 in IPFP, respectively; <i>p</i>= 0.017. 31137976 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.400 Biomarker disease BEFREE This study aimed to evaluate the association between serum vitamin D levels and nonalcoholic fatty liver disease (NAFLD) parameters, such as metabolic syndrome (MS), inflammatory cytokines (tumor necrosis factor, high sensitive C-reactive protein) and adipokines (adiponectin, leptin). 31311491 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.400 Biomarker disease BEFREE Interorgan communication by exosomes, adipose tissue, and adiponectin in metabolic syndrome. 31483293 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.400 AlteredExpression disease BEFREE To examine the prevalence of the metabolic syndrome in scholar children and to compare the degree of association of Total and High Molecular Weight adiponectin levels with biochemical parameters related to the metabolic syndrome. 31552725 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.400 Biomarker disease BEFREE Adiponectin, an adipokine secreted by adipocytes, exerts favorable effects in the milieu of diabetes and metabolic syndrome through its anti-inflammatory, antifibrotic, and antioxidant effects. 30974901 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.400 AlteredExpression disease BEFREE This finding suggests that a change in adiponectin level, as well as the baseline adiponectin level, might have a clinical role in the development of MetS among men. 31052455 2019