LIPG, lipase G, endothelial type, 9388

N. diseases: 62; N. variants: 18
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.100 GeneticVariation disease GWASCAT Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis. 30805717 2019
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis
0.100 GeneticVariation disease BEFREE The purpose of our study was to investigate the effects of endothelial lipase gene polymorphism and inflammation markers (CRP, IL-1β, IL-6, IL-8 and TNF-α) in the atherosclerosis. 23673478 2013
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.100 GeneticVariation disease BEFREE The purpose of our study was to investigate the effects of endothelial lipase gene polymorphism and inflammation markers (CRP, IL-1β, IL-6, IL-8 and TNF-α) in the atherosclerosis. 23673478 2013
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
0.100 GeneticVariation disease GWASDB Individual common variants exert weak effects on the risk for autism spectrum disorders. 22843504 2012
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE The T111I variant in the endothelial lipase gene and risk of coronary heart disease in three independent populations. 19411665 2009
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE Protective effect of an endothelial lipase gene variant on coronary artery disease in a Chinese population. 17986713 2008
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE Lack of association between a common polymorphism of the endothelial lipase gene and early-onset coronary artery disease in a Chinese Han population. 24634127 2014
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE The endothelial lipase gene (584 C/T) T allele might be protective in association with coronary artery disease. 30150432 2018
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE The associations between endothelial lipase 584C/T polymorphism and HDL-C level and coronary heart disease susceptibility: a meta-analysis. 24886585 2014
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE Associations of Rs3744841 and Rs3744843 Polymorphisms in Endothelial Lipase Gene with Risk of Coronary Artery Disease and Lipid Levels in a Chinese Population. 27612170 2016
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE Carriers of LIPG mutations exhibited trends toward reduced coronary artery disease in 4 independent cohorts (meta-analysis odds ratio, 0.7; P=0.04). 23243195 2013
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE Association of 584C/T polymorphism in endothelial lipase gene with risk of coronary artery disease. 31020688 2019
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE Endothelial lipase genetic polymorphisms and the lipid-lowering response in patients with coronary artery disease on rosuvastatin. 27600285 2016
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 GeneticVariation disease BEFREE Association of endothelial lipase gene-384A/C with coronary artery disease in Han Chinese people. 26124511 2015
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Association of endothelial lipase gene-384A/C with coronary artery disease in Han Chinese people. 26124511 2015
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Associations of Rs3744841 and Rs3744843 Polymorphisms in Endothelial Lipase Gene with Risk of Coronary Artery Disease and Lipid Levels in a Chinese Population. 27612170 2016
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Carriers of LIPG mutations exhibited trends toward reduced coronary artery disease in 4 independent cohorts (meta-analysis odds ratio, 0.7; P=0.04). 23243195 2013
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Endothelial lipase genetic polymorphisms and the lipid-lowering response in patients with coronary artery disease on rosuvastatin. 27600285 2016
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Lack of association between a common polymorphism of the endothelial lipase gene and early-onset coronary artery disease in a Chinese Han population. 24634127 2014
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE The endothelial lipase gene (584 C/T) T allele might be protective in association with coronary artery disease. 30150432 2018
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Association of 584C/T polymorphism in endothelial lipase gene with risk of coronary artery disease. 31020688 2019
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Odds ratios (ORs) with 95% confidence interval (CI) were used to evaluate the strength of the association between the EL 584C/T polymorphism and the CHD susceptibility. 24886585 2014
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Protective effect of an endothelial lipase gene variant on coronary artery disease in a Chinese population. 17986713 2008
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Small studies in selected populations have reported higher HDL-C levels among carriers of the common T111I variant in LIPG, but whether this variant is associated with plasma lipids and risk of coronary heart disease (CHD) in the general population is unclear. 19411665 2009
Low density lipoprotein cholesterol measurement
0.100 GeneticVariation phenotype GWASCAT Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program. 30275531 2018