LIPG, lipase G, endothelial type, 9388

N. diseases: 62; N. variants: 18
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020443
Disease: Hypercholesterolemia
Hypercholesterolemia
0.030 Biomarker disease BEFREE Our data indicate that in addition to variants in LDLR, APOB, PCSK9, APOE, LDLRAP1, and STAP1, variants in ABCG5/8, CYP27A1, LIPA, LIPC, and LIPG may be associated with hypercholesterolemia and such information should be used to optimize therapy. 30270055 2018
CUI: C0020443
Disease: Hypercholesterolemia
Hypercholesterolemia
0.030 AlteredExpression disease BEFREE Increased hepatic expression of EL attenuates cholesterol diet-induced hypercholesterolemia and protects against atherosclerosis. 28546217 2017
CUI: C0020443
Disease: Hypercholesterolemia
Hypercholesterolemia
0.030 AlteredExpression disease BEFREE Plasma EL levels were negatively associated with plasma HDL levels in 237 patients with cardiovascular diseases, and pitavastatin treatment reduced plasma EL levels and increased HDL-C levels in 48 patients with hypercholesterolaemia. 20045866 2010