LIPG, lipase G, endothelial type, 9388

N. diseases: 62; N. variants: 18
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.210 Biomarker group RGD Increased expression of endothelial lipase in rat models of hypertension. 15914124 2005
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.210 AlteredExpression group BEFREE Increased expression of endothelial lipase in rat models of hypertension. 15914124 2005
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.100 GeneticVariation disease GWASCAT Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis. 30805717 2019
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.100 Biomarker disease BEFREE This novel ELISA will be useful for further clarifying the impact of EL on HDL metabolism and atherosclerosis. 31473149 2019
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.100 Biomarker disease BEFREE This novel ELISA will be useful for further clarifying the impact of EL on HDL metabolism and atherosclerosis. 31473149 2019
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.100 GeneticVariation disease BEFREE Association of 584C/T polymorphism in endothelial lipase gene with risk of coronary artery disease. 31020688 2019
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.100 Biomarker disease BEFREE The full and total EL mass were measured in 556 patients with coronary artery disease. 31473149 2019
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.100 Biomarker disease BEFREE The full and total EL mass were measured in 556 patients with coronary artery disease. 31473149 2019
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.100 GeneticVariation disease BEFREE Association of 584C/T polymorphism in endothelial lipase gene with risk of coronary artery disease. 31020688 2019
CUI: C0392885
Disease: High density lipoprotein measurement
High density lipoprotein measurement 		0.100 GeneticVariation phenotype GWASCAT Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis. 30805717 2019
CUI: C0427460
Disease: Red cell distribution width determination
Red cell distribution width determination 		0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C1304746
Disease: RDW - Red blood cell distribution width result
RDW - Red blood cell distribution width result 		0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.100 Biomarker disease BEFREE The full and total EL mass were measured in 556 patients with coronary artery disease. 31473149 2019
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.100 Biomarker disease BEFREE Serum EL and HL concentrations were both significantly increased in patients with CAD or in-stent restenosis, whereas serum LPL concentration was reduced significantly in patients with CAD. 30651409 2019
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.100 GeneticVariation disease BEFREE Association of 584C/T polymorphism in endothelial lipase gene with risk of coronary artery disease. 31020688 2019
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.100 Biomarker disease BEFREE Inhibition of EL has been shown to increase HDL concentration in preclinical animal models and was targeted as a potential treatment of atherosclerosis. 30613337 2018
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.100 Biomarker disease BEFREE Thus far, the extensive investigations of LIPG have focused on its mechanisms and involvement in metabolic syndromes such as atherosclerosis. 28540715 2018
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.100 AlteredExpression disease BEFREE Endothelial lipase (EL) reportedly reduces HDL levels, which, in theory, would increase atherosclerosis. 29748333 2018
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.100 Biomarker disease BEFREE Inhibition of EL has been shown to increase HDL concentration in preclinical animal models and was targeted as a potential treatment of atherosclerosis. 30613337 2018
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.100 Biomarker disease BEFREE Thus far, the extensive investigations of LIPG have focused on its mechanisms and involvement in metabolic syndromes such as atherosclerosis. 28540715 2018
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.100 AlteredExpression disease BEFREE Endothelial lipase (EL) reportedly reduces HDL levels, which, in theory, would increase atherosclerosis. 29748333 2018
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.100 GeneticVariation disease BEFREE The endothelial lipase gene (584 C/T) T allele might be protective in association with coronary artery disease. 30150432 2018
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.100 GeneticVariation disease BEFREE The endothelial lipase gene (584 C/T) T allele might be protective in association with coronary artery disease. 30150432 2018
CUI: C0202117
Disease: Low density lipoprotein cholesterol measurement
Low density lipoprotein cholesterol measurement 		0.100 GeneticVariation phenotype GWASCAT Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program. 30275531 2018
CUI: C0392885
Disease: High density lipoprotein measurement
High density lipoprotein measurement 		0.100 GeneticVariation phenotype GWASCAT A large electronic-health-record-based genome-wide study of serum lipids. 29507422 2018