FOXQ1, forkhead box Q1, 94234

N. diseases: 67; N. variants: 0
Disease: Breast Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.340 Biomarker disease BEFREE These data suggest that targeting of the novel miR-937-FOXQ1 axis is an attractive therapeutic method against breast cancer. 31417280 2019
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.340 Biomarker disease CTD_human Expression profiling for cancer stem cell-related genes suggested that FoxQ1 may negatively regulate the expression of Dachshund homolog 1 (DACH1), whose expression is lost in invasive breast cancer. 27129776 2016
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.340 AlteredExpression disease BEFREE Moreover, an inverse association was observed between FoxQ1 and DACH1 gene expression in breast cancer cell lines and tumors. 27129776 2016
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.340 AlteredExpression disease BEFREE In this study, we defined a critical functional role for the Forkhead transcription factor FOXQ1 in regulating EMT in breast cancer cells. 21346143 2011
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.340 Biomarker disease BEFREE Our findings highlight the feasibility of cross-species expression profiling as a strategy to identify metastasis-related genes, and they reveal that EMT induction is a likely mechanism underlying a novel metastasis-promoting function of Foxq1 defined here in breast cancer. 21285253 2011