FOXQ1, forkhead box Q1, 94234

N. diseases: 67; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.060 AlteredExpression disease BEFREE In the present study, we reveal that CAFs induce forkhead box Q1 (FOXQ1) expression, and N-myc downstream-regulated gene 1 (NDRG1) is therefore trans-activated to enhance HCC initiation. 29248714 2018
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.060 AlteredExpression disease BEFREE The subgroup analysis suggested that the elevated levels of FOXQ1 appear to be associated with worse OS in hepatocellular carcinoma (HR =1.34; 95% CI: 1.11-1.57; <i>P</i><0.001) and other cancers (HR =1.62; 95% CI: 1.09-2.14; <i>P</i><0.001). 28367060 2017
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.060 Biomarker disease BEFREE A mechanistic study identified three genes, forkhead box G1 (FOXG1), FOXQ1, and FOXE1, as miR-422a targets in the regulation of HCC development. 25251503 2015
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.060 Biomarker disease BEFREE Our data indicated that both Foxp1 and Foxq1 genes played an oncogenic role in hepatocarcinoma cells, which proposed the two genes as new therapeutic targets for the cancer. 24211718 2014
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.060 AlteredExpression disease BEFREE Knockdown of ZEB2 decreased FoxQ1-enhanced HCC metastasis, whereas up-regulation of ZEB2 rescued the decreased metastasis induced by FoxQ1 knocking down. 24005989 2014
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.060 AlteredExpression disease BEFREE Finally, we analyzed FOXQ1 expression and clinicopathological factors in 114 HCC patients using SPSS 20.0 software. 23623360 2013