Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.100 Biomarker group BEFREE In all 3 cases, biopsy, histology, and immunohistochemistry using a panel of lymphoid markers (Epstein-Barr virus [EBV], CD79a, CD20, PAX-5, CD3, and CD30) resulted in the diagnosis of EBV-driven T-cell, B-cell, and Hodgkin-like LPD. 28654766 2018
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.100 Biomarker group BEFREE In 6 patients, a diagnosis of CD30+ lymphoproliferative disorder or Sézary syndrome was proposed or suspected histopathologically, and only the clinical context allowed the diagnosis of ELR with a peculiar presentation with atypical lymphocytes. 29107664 2018
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.100 Biomarker group BEFREE CD30+ pseudolymphoma should be distinguished from malignant intravascular lymphoproliferative disorders. 29369392 2018
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.100 Biomarker group BEFREE CD8-positive, CD30-positive cutaneous lymphoproliferative disorders constitute a rare subset of T-cell lymphoproliferative conditions, including variants of primary cutaneous anaplastic large cell lymphoma (ALCL), mycosis fungoides, lymphomatoid papulosis type D, cutaneous gamma-delta T-cell lymphoma and cutaneous peripheral T-cell lymphoma. 28497585 2017
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.100 AlteredExpression group BEFREE CD30 Expression in Monomorphic Posttransplant Lymphoproliferative Disorder, Diffuse Large B-Cell Lymphoma Correlates With Greater Regulatory T-Cell Infiltration. 29126177 2017
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.100 Biomarker group BEFREE Hepatitis E virus-induced primary cutaneous CD30(+) T cell lymphoproliferative disorder. 28860025 2017
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.100 Biomarker group BEFREE Sinusoidal CD30+ diffuse large B-cell lymphoma can masquerade as anaplastic large cell lymphoma in pediatric posttransplant lymphoproliferative disorders. 28035754 2017
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.100 Biomarker group BEFREE It represents a potential treatment for the CD30+ lymphoproliferative disorder lymphomatoid papulosis (LyP), which currently has no approved treatment. 28980004 2017
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.100 Biomarker group BEFREE Expression of CD30 in blastoid cutaneous infiltrates typically signifies a CD30 lymphoproliferative disorder, often requiring minimal immunohistochemical workup, if clinically consonant. 27893466 2017
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.100 Biomarker group BEFREE A new era for cutaneous CD30-positive T-cell lymphoproliferative disorders. 27993440 2017
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.100 AlteredExpression group BEFREE Moreover, as CD30 antigen may be expressed by other malignancies, the potential therapeutic application is increasing, including at least diffuse large B-cell lymphoma, T-cell lymphomas other than ALCL and cutaneous lymphoproliferative disorders. 27592544 2017
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.100 Biomarker group BEFREE Diagnosis of PC-ALCL relies strongly on clinicopathologic correlation given the potential morphologic, clinical and molecular overlap with the other cutaneous CD30+ LPD, lymphomatoid papulosis, and more aggressive hematolymphoid neoplasms. 28342276 2017
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.100 AlteredExpression group BEFREE CD30 is a tumor necrosis factor receptor (TNFR) family member whose expression is associated with Hodgkin's disease, anaplastic large cell lymphomas, and other T and B lymphoproliferative disorders in humans. 28993768 2017
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.100 Biomarker group BEFREE The extent of CD30 positivity in SMPTCL needs to be defined further along with its association with other forms of CD30+ lymphoproliferative disease including its potential categorization as a form of endogenous CD30+ lymphoproliferative disease. 28965629 2017
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.100 Biomarker group BEFREE Mycosis fungoides (MF) is the most common primary cutaneous T-cell lymphoma (CTCL), followed by CD30+ lymphoproliferative disorders, including lymphomatoid papulosis (LyP) and primary cutaneous anaplastic large cell lymphoma (pcALCL). 26266670 2016
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.100 AlteredExpression group BEFREE We studied CD30 expression in types of aggressive B-cell lymphomas not previously studied, including Burkitt lymphoma, high-grade (grade III) follicular lymphoma, mixed grade III follicular lymphoma/diffuse large B-cell lymphoma (DLBCL), posttransplantation lymphoproliferative disease large B-cell lymphoma, and primary mediastinal large B-cell lymphoma. 27521276 2016
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.100 Biomarker group BEFREE TOX staining was performed in MF, CD30(+) LPD, LPP as well as benign inflammatory dermatoses (BID) and normal skin (NS). 27345620 2016
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.100 Biomarker group BEFREE CD30-positive primary cutaneous lymphoproliferative disorders include several entities with differing clinical presentation but overlapping histological features, including lymphomatoid papulosis and primary cutaneous anaplastic large cell lymphoma (C-ALCL). 25131361 2015
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.100 Biomarker group BEFREE Once a diagnosis of lymphoma is established, it is important to exclude systemic anaplastic lymphoma kinase-negative ALCL involving the breast, primary cutaneous ALCL, and other CD30(+) lymphoproliferative disorders. 24878027 2014
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.100 Biomarker group BEFREE Therefore, we aimed to analyze the expression of 5-hmC in cutaneous CD30-positive lymphoproliferative disorders and compare it with a control group composed of reactive infectious and inflammatory disorders with CD30-positive cells. 25353265 2014
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.100 Biomarker group BEFREE Intralymphatic cutaneous anaplastic large cell lymphoma/lymphomatoid papulosis: expanding the spectrum of CD30-positive lymphoproliferative disorders. 24805854 2014
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.100 Biomarker group BEFREE This is the first report of recurrent translocations involving TYK2, and it highlights the novel therapeutic opportunities in the treatment of CD30-positive LPDs with TYK2 translocations. 25349176 2014
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.100 Biomarker group BEFREE SATB1 overexpression promotes malignant T-cell proliferation in cutaneous CD30+ lymphoproliferative disease by repressing p21. 24747435 2014
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.100 Biomarker group BEFREE Lymphomatoid papulosis (LyP) belongs to the spectrum of primary cutaneous CD30-positive lymphoproliferative disorders. 23026936 2013
CUI: C0024314
Disease: Lymphoproliferative Disorders
Lymphoproliferative Disorders
0.100 Biomarker group BEFREE Primary cutaneous anaplastic large cell lymphoma is regarded as an ALK-negative variant confined to the skin and is part of the spectrum of primary cutaneous CD30-positive T-cell lymphoproliferative disorders. 22773605 2013