|
Enterovirus Infections
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2.
|
30531980 |
2019 |
|
Enterovirus Infections
|
0.100 |
Biomarker
|
group |
BEFREE |
Severity of enterovirus A71 infection in a human SCARB2 knock-in mouse model is dependent on infectious strain and route.
|
30518755 |
2018 |
|
Enterovirus Infections
|
0.100 |
Biomarker
|
group |
BEFREE |
A CpG-adjuvanted intranasal enterovirus 71 vaccine elicits mucosal and systemic immune responses and protects human SCARB2-transgenic mice against lethal challenge.
|
30013088 |
2018 |
|
Enterovirus Infections
|
0.100 |
GeneticVariation
|
group |
BEFREE |
To evaluate the association of enterovirus 71 (EV71) susceptibility and clinical severity with polymorphisms in EV71 receptors, including human scavenger receptor class B member 2 (SCARB2), P-selectin glycoprotein ligand-1 (PSGL-1), and annexin II (ANXA2).
|
30395634 |
2018 |
|
Enterovirus Infections
|
0.100 |
Biomarker
|
group |
BEFREE |
The atomic-resolution structure of the CVA10 virion, which is within the KREMEN1-dependent subgroup, shows significant conformational differences in the putative receptor binding sites and serotype-specific epitopes, when compared to the SCARB2-dependent subgroup of HEV-A, such as EV71, highlighting specific differences between the sub-groups.
|
30478256 |
2018 |
|
Enterovirus Infections
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Furthermore, immunohistochemistry was conducted to detect the distribution and expression level of two enterovirus 71 (EV71) receptors scavenger receptor class B, member 2 (SCARB2), and P-selectin glycoprotein ligand-1 (PSGL1) in the samples of autopsies.
|
28756983 |
2017 |
|
Enterovirus Infections
|
0.100 |
Biomarker
|
group |
BEFREE |
A safe and sensitive enterovirus A71 infection model based on human SCARB2 knock-in mice.
|
27102822 |
2016 |
|
Enterovirus Infections
|
0.100 |
Biomarker
|
group |
BEFREE |
Motor coordination and balance measurements reveal differential pathogenicity of currently spreading enterovirus 71 strains in human SCARB2 transgenic mice.
|
27902385 |
2016 |
|
Enterovirus Infections
|
0.100 |
Biomarker
|
group |
BEFREE |
The lysosomal integral membrane protein type-2 (LIMP-2/SCARB2) has been identified as a receptor for enterovirus 71 uptake and mannose-6-phosphate-independent lysosomal trafficking of the acid hydrolase β-glucocerebrosidase.
|
25576872 |
2015 |
|
Enterovirus Infections
|
0.100 |
Biomarker
|
group |
BEFREE |
However, the LIMP-2/SCARB2 binding sequences for enterovirus 71 and GCase are not similar, indicating that LIMP-2/SCARB2 may have multiple or overlapping binding sites with differing specificities.
|
25202012 |
2014 |
|
Enterovirus Infections
|
0.100 |
Biomarker
|
group |
BEFREE |
The aim of this study was to investigate the distribution of Enterovirus 71 (EV71) receptors SCARB2 and PSGL-1 in human tissues.
|
24997419 |
2014 |
|
Enterovirus Infections
|
0.100 |
Biomarker
|
group |
BEFREE |
Human SCARB2 transgenic mice as an infectious animal model for enterovirus 71.
|
23451246 |
2013 |
|
Enterovirus Infections
|
0.100 |
Biomarker
|
group |
BEFREE |
Human SCARB2-dependent infection by coxsackievirus A7, A14, and A16 and enterovirus 71.
|
22438546 |
2012 |