CD59, CD59 molecule (CD59 blood group), 966

N. diseases: 262; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0152025
Disease: Polyneuropathy
Polyneuropathy
0.120 GeneticVariation disease BEFREE Mutations in CD59 cause CIDP-like polyneuropathy in children with inherited chronic hemolysis. 30794663 2019
CUI: C0152025
Disease: Polyneuropathy
Polyneuropathy
0.120 GeneticVariation disease BEFREE While paroxysmal nocturnal hemoglobinuria (PNH) results from the combined deficiency of the regulatory complement proteins CD55 and CD59, which is caused by somatic mutation of a common membrane anchor, isolated CD55 or CD59 deficiency is associated with the CHAPLE syndrome and polyneuropathy, respectively. 31421540 2019
CUI: C0152025
Disease: Polyneuropathy
Polyneuropathy
0.120 Biomarker disease HPO