Acrania
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Here, we show that Cart1-homozygous mutant mice are born alive with acrania and meroanencephaly but die soon after birth-a phenotype that strikingly resembles a corresponding human syndrome caused by a neural tube closure defect.
|
8673125 |
1996 |
Breast Carcinoma
|
0.040 |
Biomarker
|
disease |
BEFREE |
Altogether, these observations indicate that CART1 may be involved in TNF-related cytokine signal transduction in breast carcinoma.
|
7592751 |
1995 |
Breast Carcinoma
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
Increased Eps15 homology domain 1 and RAB11FIP3 expression regulate breast cancer progression via promoting epithelial growth factor receptor recycling.
|
28215104 |
2017 |
Breast Carcinoma
|
0.040 |
Biomarker
|
disease |
BEFREE |
Rab11-FIP3 is a Rab11-binding protein that regulates breast cancer cell motility by modulating the actin cytoskeleton.
|
19327867 |
2009 |
Breast Carcinoma
|
0.040 |
Biomarker
|
disease |
BEFREE |
Our results suggest that: (a) an independent, amplified region defined by MLN 62 (also called CART1 or TRAF4) is located in 17q11-q12; (b) in addition to ERBB2, MLN 64 is a major target for the 17q12-q21 amplicon; and (c) these MLN genes could be of pathogenetic significance in breast cancer.
|
8752152 |
1996 |
Cervix carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Here we report the molecular cloning of the human Cart-1 cDNA from a HeLa cervical carcinoma cDNA library.
|
8756334 |
1996 |
Chondrosarcoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Cart-1 cDNA was recently cloned from a rat chondrosarcoma tumor and it encodes a protein containing a paired-like homeodomain that is selectively expressed in cartilage during early chondrocyte differentiation.
|
8756334 |
1996 |
Exencephaly
|
0.010 |
Biomarker
|
disease |
BEFREE |
Among responsive mutants, folic acid supplementation reduces exencephaly and/or spina bifida aperta frequency in the Sp(2H), Sp, Cd, Cited2, Cart1, and Gcn5 mutants.Prevention ranges from 35 to 85%.
|
19117321 |
2009 |
Finding of Mean Corpuscular Hemoglobin
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
|
29403010 |
2018 |
HBV coinfection
|
0.010 |
Biomarker
|
disease |
BEFREE |
Lamivudine Monotherapy-Based cART Is Efficacious for HBV Treatment in HIV/HBV Coinfection When Baseline HBV DNA <20,000 IU/mL.
|
26745828 |
2016 |
Malignant neoplasm of breast
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
Increased Eps15 homology domain 1 and RAB11FIP3 expression regulate breast cancer progression via promoting epithelial growth factor receptor recycling.
|
28215104 |
2017 |
Malignant neoplasm of breast
|
0.030 |
Biomarker
|
disease |
BEFREE |
Rab11-FIP3 is a Rab11-binding protein that regulates breast cancer cell motility by modulating the actin cytoskeleton.
|
19327867 |
2009 |
Malignant neoplasm of breast
|
0.030 |
Biomarker
|
disease |
BEFREE |
Our results suggest that: (a) an independent, amplified region defined by MLN 62 (also called CART1 or TRAF4) is located in 17q11-q12; (b) in addition to ERBB2, MLN 64 is a major target for the 17q12-q21 amplicon; and (c) these MLN genes could be of pathogenetic significance in breast cancer.
|
8752152 |
1996 |
Mean Corpuscular Volume (result)
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
|
29403010 |
2018 |
Neoplasm Metastasis
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
CART1 is specifically expressed by epithelial cells in breast carcinomas and metastases.
|
7592751 |
1995 |
Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
Cart-1 cDNA was recently cloned from a rat chondrosarcoma tumor and it encodes a protein containing a paired-like homeodomain that is selectively expressed in cartilage during early chondrocyte differentiation.
|
8756334 |
1996 |
Neural Tube Defects
|
0.020 |
Biomarker
|
group |
BEFREE |
In genetic NTD models such as Cart1, splotch, Cited2, and crooked tail, and NTD induced by teratogens including valproic acid and fumonisins, the incidence of defects is reduced by maternal folic acid supplementation.
|
15800852 |
2005 |
Neural Tube Defects
|
0.020 |
Biomarker
|
group |
BEFREE |
Mutations in transcriptional co-activator genes-Cited2, p300, Cbp, Tfap2α, Carm1 and Cart1 result in NTDs in murine models, thus prompt us to investigate whether homologues of these genes are associated with NTDs in humans.
|
20932315 |
2010 |
Papillary thyroid carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
EHD1, EGFR, CAV-1 and RAB11FIP3 expression levels were increased in human PTC.
|
30214560 |
2018 |
Platelet Component Distribution Width Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
Platelet Count measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
Secondary malignant neoplasm of lymph node
|
0.010 |
Biomarker
|
disease |
BEFREE |
EGFR was only associated with lymph node metastasis (P=0.027) and RAB11FIP3 was not associated with any clinicopathological characteristics.
|
30214560 |
2018 |
Secondary Neoplasm
|
0.010 |
AlteredExpression
|
group |
BEFREE |
CART1 is specifically expressed by epithelial cells in breast carcinomas and metastases.
|
7592751 |
1995 |
Spina Bifida Cystica
|
0.010 |
Biomarker
|
disease |
BEFREE |
Among responsive mutants, folic acid supplementation reduces exencephaly and/or spina bifida aperta frequency in the Sp(2H), Sp, Cd, Cited2, Cart1, and Gcn5 mutants.Prevention ranges from 35 to 85%.
|
19117321 |
2009 |