CKAP5, cytoskeleton associated protein 5, 9793

N. diseases: 10; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002938
Disease: Aneuploidy
Aneuploidy
0.300 Biomarker phenotype CTD_human Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells. 24976383 2014
CUI: C1257806
Disease: Chromosomal Instability
Chromosomal Instability
0.300 Biomarker phenotype CTD_human Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells. 24976383 2014
CUI: C0005938
Disease: Bone Density
Bone Density
0.100 GeneticVariation phenotype GWASCAT Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects. 29304378 2018
CUI: C2239219
Disease: von Willebrand's factor (lab test)
von Willebrand's factor (lab test)
0.100 GeneticVariation phenotype GWASDB Ischemic stroke is associated with the ABO locus: the EuroCLOT study. 23381943 2013
CUI: C0005938
Disease: Bone Density
Bone Density
0.100 GeneticVariation phenotype GWASCAT New sequence variants associated with bone mineral density. 19079262 2009
CUI: C0005938
Disease: Bone Density
Bone Density
0.100 GeneticVariation phenotype GWASDB New sequence variants associated with bone mineral density. 19079262 2009
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.020 Biomarker disease BEFREE The aim of the present study was to explore the association between the expression profiles of Aurora kinases (<i>AURKA</i>, <i>AURKB</i> and <i>AURKC</i>), cytoskeleton-associated protein 5 (<i>CKAP5</i>), discs large-associated protein 5 (<i>DLGAP5</i>), kinesin-like protein 11 (<i>KIF11</i>), microtubule nucleation factor (<i>TPX2</i>), monopolar spindle 1 kinase (<i>TTK</i>), and β-tubulins (<i>TUBB</i>) and (<i>TUBB3</i>) genes and clinicopathological characteristics in human non-small cell lung carcinoma (NSCLC). 28588715 2017
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.020 Biomarker disease BEFREE Taken together, our data demonstrate that the expression of the mitosis-associated genes AURKA, DLGAP5, TPX2, KIF11 and CKAP5 is associated with the prognosis of NSCLC patients. 28101582 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.020 AlteredExpression group BEFREE The tumor overexpressed gene (TOG) protein is present in RNA granules that transport myelin basic protein (MBP) mRNA in oligodendrocyte processes to the myelin compartment. 28063167 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.020 AlteredExpression group BEFREE Expression of the tumor over-expressed ch-TOG gene in human and baboon brain. 8832653 1996
CUI: C0018081
Disease: Gonorrhea
Gonorrhea
0.010 Biomarker disease BEFREE Gentamicin as an alternative to ceftriaxone in the treatment of gonorrhoea: the G-TOG non-inferiority RCT. 31099330 2019
CUI: C0017638
Disease: Glioma
Glioma
0.010 Biomarker disease BEFREE Cytoskeleton-associated protein 5 (CKAP5) was identified as an interaction protein of ARHGEF16, which is important for the stimulatory effects of ARHGEF16 on glioma cell migration and proliferation. 30305138 2018
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.010 Biomarker group BEFREE Our data suggest that eribulin binding to the tip of microtubules and subsequent loss of ch-TOG is a priming event leading to alterations in microtubule dynamics and cancer cell migration. 26497677 2015
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker group BEFREE Our data suggest that eribulin binding to the tip of microtubules and subsequent loss of ch-TOG is a priming event leading to alterations in microtubule dynamics and cancer cell migration. 26497677 2015