CDK1, cyclin dependent kinase 1, 983

N. diseases: 214; N. variants: 8
Disease: Liver neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.240 Biomarker group RGD Forkhead box M1B is a determinant of rat susceptibility to hepatocarcinogenesis and sustains ERK activity in human HCC. 19136513 2009
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.240 Biomarker group BEFREE G2-phase arrest through p21(WAF1 / Cip1) induction and cdc2 repression by gnidimacrin in human hepatoma HLE cells. 19414386 2009
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.240 PosttranslationalModification group BEFREE SarCNU-induced G2/M arrest in hepatoma cells is mediated by a p53-independent phosphorylation of cdc-2 at Tyr15. 15754328 2005
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.240 Biomarker group BEFREE Flow cytometry showed that genistein, but not biochanin-A or daidzein, induced progressive and sustained accumulation of hepatoma cancer cells in the G2/M phase as a result of inhibition of Cdc2 kinase activity. 12791511 2003
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.240 AlteredExpression group BEFREE Induction of p21(CIP1/Waf1) and activation of p34(cdc2) involved in retinoic acid-induced apoptosis in human hepatoma Hep3B cells. 10094816 1999