Nematode infections
0.010
Biomarker
group
BEFREE
The predicted WDR1 protein has high sequence identity to WD40-repeat proteins in budding yeast (Saccharomyces cerevisiae), two slime molds (Dictyostelium discoideum and Physarum polycephalum), and the roundworm (Caenorhabditis elegans).
10036186
1999
Malignant melanoma of eye
0.010
Biomarker
disease
BEFREE
Ca2+ binding to EF hands 1 and 3 is essential for the interaction of apoptosis-linked gene-2 with Alix/AIP1 in ocular melanoma .
15366927
2004
Thrombocytopenia
0.310
Biomarker
phenotype
CTD_human
Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia.
17515402
2007
Inflammation
0.300
Biomarker
phenotype
CTD_human
Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia.
17515402
2007
Macrothrombocytopenia
0.010
GeneticVariation
disease
BEFREE
Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia .
17515402
2007
Autoinflammatory disease
0.010
GeneticVariation
disease
BEFREE
Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia.
17515402
2007
Osteoporosis, Age-Related
0.300
Biomarker
disease
CTD_human
Proteomic analysis of circulating monocytes in Chinese premenopausal females with extremely discordant bone mineral density.
18924182
2008
Osteoporosis
0.300
Biomarker
disease
CTD_human
Proteomic analysis of circulating monocytes in Chinese premenopausal females with extremely discordant bone mineral density.
18924182
2008
Osteoporosis, Senile
0.300
Biomarker
disease
CTD_human
Proteomic analysis of circulating monocytes in Chinese premenopausal females with extremely discordant bone mineral density.
18924182
2008
Post-Traumatic Osteoporosis
0.300
Biomarker
disease
CTD_human
Proteomic analysis of circulating monocytes in Chinese premenopausal females with extremely discordant bone mineral density.
18924182
2008
Schizophrenia
0.010
AlteredExpression
disease
LHGDN
Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.
19165527
2009
Uric acid measurement (procedure)
0.100
GeneticVariation
phenotype
GWASDB
Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.
19503597
2009
Arthritis, Gouty
0.100
GeneticVariation
disease
GWASDB
Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors.
20884846
2010
×
CUI:
C0018099
Disease:
Gout
Gout
0.100
GeneticVariation
disease
GWASDB
Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors.
20884846
2010
Arteriosclerosis
0.050
Biomarker
disease
BEFREE
AIP1 prevents graft arteriosclerosis by inhibiting interferon-γ-dependent smooth muscle cell proliferation and intimal expansion.
21700930
2011
Arthritis, Gouty
0.100
GeneticVariation
disease
GWASDB
Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele.
21768215
2011
×
CUI:
C0018099
Disease:
Gout
Gout
0.100
GeneticVariation
disease
GWASDB
Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele.
21768215
2011
Malignant neoplasm of lung
0.020
GeneticVariation
disease
BEFREE
A common genetic variant (97906C>A) of DAB2IP/AIP1 is associated with an increased risk and early onset of lung cancer in Chinese males.
22046421
2011
Carcinoma of lung
0.020
GeneticVariation
disease
BEFREE
A common genetic variant (97906C>A) of DAB2IP/AIP1 is associated with an increased risk and early onset of lung cancer in Chinese males.
22046421
2011
Primary malignant neoplasm of lung
0.020
GeneticVariation
disease
BEFREE
A common genetic variant (97906C>A) of DAB2IP/AIP1 is associated with an increased risk and early onset of lung cancer in Chinese males.
22046421
2011
Thyroid Neoplasm
0.010
Biomarker
disease
BEFREE
The aim of this study was to isolate an autoantibody to tumour antigen, WD repeat domain 1 (WDR1 ), and evaluate its diagnostic sensitivity and specificity for thyroid neoplasms .
23215816
2013
Anaplastic thyroid carcinoma
0.010
Biomarker
disease
BEFREE
Using a serological analysis of recombinant cDNA expression cloning (SEREX) strategy, we isolated WDR1 and its specific autoantibody in the sera of patients with undifferentiated thyroid carcinoma (UTC ).
23215816
2013
Papillary thyroid carcinoma
0.010
Biomarker
disease
BEFREE
Anti-WDR1 antibody could be a novel approach for serological screening of PTC and UTC, and could be an efficient and inexpensive biomarker.
23215816
2013
Arthritis, Gouty
0.100
GeneticVariation
disease
GWASDB
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
23263486
2013
×
CUI:
C0018099
Disease:
Gout
Gout
0.100
GeneticVariation
disease
GWASDB
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
23263486
2013