DisGeNET - a database of gene-disease associations

NR1H4, nuclear receptor subfamily 1 group H member 4, 9971

N. diseases: 187; N. variants: 6

Disease: Chemical and Drug Induced Liver Injury ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Disease

Score _gda

Association Type

Type

Original DB

Sentence supporting the association

PMID

PMID Year

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.500

Biomarker

disease

RGD

Dose-related liver injury of Geniposide associated with the alteration in bile acid synthesis and transportation.

28827769

2017

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.500

Biomarker

disease

CTD_human

[Functional analysis of drug metabolizing enzymes using gene knockout animals].

12875239

2003

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.500

ModifyingMutation

disease

RGD

Dysregulation of BSEP and MRP2 May Play an Important Role in Isoniazid-Induced Liver Injury via the SIRT1/FXR Pathway in Rats and HepG2 Cells.

30068870

2018