Hereditary Diffuse Gastric Cancer
|
0.800 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
|
|
|
Hereditary Diffuse Gastric Cancer
|
0.800 |
Biomarker
|
disease |
CLINGEN |
Expression of E- and P-cadherin in gastric carcinomas.
|
2009537 |
1991 |
Hereditary Diffuse Gastric Cancer
|
0.800 |
Biomarker
|
disease |
CLINGEN |
Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role.
|
2070412 |
1991 |
Hereditary Diffuse Gastric Cancer
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
Localization of specificity determining sites in cadherin cell adhesion molecules.
|
2317870 |
1990 |
Hereditary Diffuse Gastric Cancer
|
0.800 |
GeneticVariation
|
disease |
CLINVAR |
E-cadherin gene mutations in human gastric carcinoma cell lines.
|
8127895 |
1994 |
Hereditary Diffuse Gastric Cancer
|
0.800 |
Biomarker
|
disease |
CLINGEN |
From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion.
|
8236461 |
1993 |
Hereditary Diffuse Gastric Cancer
|
0.800 |
Biomarker
|
disease |
CLINGEN |
A causal role for E-cadherin in the transition from adenoma to carcinoma.
|
9515965 |
1998 |
Hereditary Diffuse Gastric Cancer
|
0.800 |
Biomarker
|
disease |
CTD_human |
E-cadherin germline mutations in familial gastric cancer.
|
9537325 |
1998 |
Hereditary Diffuse Gastric Cancer
|
0.800 |
Biomarker
|
disease |
CLINGEN |
E-cadherin germline mutations in familial gastric cancer.
|
9537325 |
1998 |
Hereditary Diffuse Gastric Cancer
|
0.800 |
GeneticVariation
|
disease |
CLINVAR |
E-cadherin germline mutations in familial gastric cancer.
|
9537325 |
1998 |
Hereditary Diffuse Gastric Cancer
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
Identification of germ-line E-cadherin mutations in gastric cancer families of European origin.
|
9751616 |
1998 |
Hereditary Diffuse Gastric Cancer
|
0.800 |
GeneticVariation
|
disease |
CLINVAR |
Coupling assembly of the E-cadherin/beta-catenin complex to efficient endoplasmic reticulum exit and basal-lateral membrane targeting of E-cadherin in polarized MDCK cells.
|
10037790 |
1999 |
Hereditary Diffuse Gastric Cancer
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
We have confirmed that germline mutations in the CDH1 gene cause familial gastric cancer in non-Maori populations.
|
10072428 |
1999 |
Hereditary Diffuse Gastric Cancer
|
0.800 |
Biomarker
|
disease |
CTD_human |
We have confirmed that germline mutations in the CDH1 gene cause familial gastric cancer in non-Maori populations.
|
10072428 |
1999 |
Hereditary Diffuse Gastric Cancer
|
0.800 |
Biomarker
|
disease |
CLINGEN |
We have confirmed that germline mutations in the CDH1 gene cause familial gastric cancer in non-Maori populations.
|
10072428 |
1999 |
Hereditary Diffuse Gastric Cancer
|
0.800 |
GeneticVariation
|
disease |
BEFREE |
We have confirmed that germline mutations in the CDH1 gene cause familial gastric cancer in non-Maori populations.
|
10072428 |
1999 |
Hereditary Diffuse Gastric Cancer
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
Identification of eleven novel tumor-associated E-cadherin mutations. Mutations in brief no. 215. Online.
|
10094558 |
1999 |
Hereditary Diffuse Gastric Cancer
|
0.800 |
GeneticVariation
|
disease |
UNIPROT |
We screened five Korean familial gastric cancer patients to investigate germline mutations of the E-cadherin gene.
|
10319582 |
1999 |
Hereditary Diffuse Gastric Cancer
|
0.800 |
GeneticVariation
|
disease |
BEFREE |
However, no germ-line mutation was detected, suggesting that a predisposition to FGCs by E-cadherin gene mutation is infrequent in Japanese cases.
|
10389930 |
1999 |
Hereditary Diffuse Gastric Cancer
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
Diffuse type gastric and lobular breast carcinoma in a familial gastric cancer patient with an E-cadherin germline mutation.
|
10433926 |
1999 |
Hereditary Diffuse Gastric Cancer
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
E-cadherin germline mutations define an inherited cancer syndrome dominated by diffuse gastric cancer.
|
10477433 |
1999 |
Hereditary Diffuse Gastric Cancer
|
0.800 |
GeneticVariation
|
disease |
CLINVAR |
E-cadherin germline mutations define an inherited cancer syndrome dominated by diffuse gastric cancer.
|
10477433 |
1999 |
Hereditary Diffuse Gastric Cancer
|
0.800 |
GeneticVariation
|
disease |
BEFREE |
These results demonstrate that germline mutation of the E-cadherin gene is a common cause of hereditary diffuse gastric cancer and suggest a role for these mutations in the incidence of breast cancer.
|
10477433 |
1999 |
Hereditary Diffuse Gastric Cancer
|
0.800 |
GeneticVariation
|
disease |
BEFREE |
More recently, germline E-cadherin/CDH1 mutations have been identified in hereditary diffuse gastric cancer kindred.
|
10593993 |
1999 |
Hereditary Diffuse Gastric Cancer
|
0.800 |
PosttranslationalModification
|
disease |
BEFREE |
Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer.
|
10973239 |
2000 |