ADRA2A, adrenoceptor alpha 2A, 150

N. diseases: 102; N. variants: 7
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs553668
rs553668 		0.807 0.160 10 111079821 3 prime UTR variant A/G;T snv
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.050 1.000 5 2011 2018
dbSNP: rs1800544
rs1800544 		0.790 0.160 10 111076745 upstream gene variant G/C snv 0.59
CUI: C1263846
Disease: Attention deficit hyperactivity disorder
Attention deficit hyperactivity disorder 		Mental Disorders 0.020 1.000 2 2010 2014
dbSNP: rs1800544
rs1800544 		0.790 0.160 10 111076745 upstream gene variant G/C snv 0.59
CUI: C0029456
Disease: Osteoporosis
Osteoporosis 		Nutritional and Metabolic Diseases; Musculoskeletal Diseases 0.020 1.000 2 2015 2018
dbSNP: rs1800035
rs1800035 		0.925 0.080 10 111078794 missense variant C/G;T snv 1.9E-03
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		Mental Disorders 0.010 < 0.001 1 2006 2006
dbSNP: rs1800035
rs1800035 		0.925 0.080 10 111078794 missense variant C/G;T snv 1.9E-03
CUI: C0424295
Disease: Hyperactive behavior
Hyperactive behavior 		Pathological Conditions, Signs and Symptoms; Nervous System Diseases 0.010 < 0.001 1 2006 2006
dbSNP: rs1800035
rs1800035 		0.925 0.080 10 111078794 missense variant C/G;T snv 1.9E-03
CUI: C0344315
Disease: Depressed mood
Depressed mood 		Behavior and Behavior Mechanisms 0.010 < 0.001 1 2006 2006
dbSNP: rs1800035
rs1800035 		0.925 0.080 10 111078794 missense variant C/G;T snv 1.9E-03
CUI: C0011570
Disease: Mental Depression
Mental Depression 		Behavior and Behavior Mechanisms 0.010 < 0.001 1 2006 2006
dbSNP: rs1800038
rs1800038 		10 111079134 synonymous variant C/A snv 7.4E-02 4.9E-02
CUI: C0085207
Disease: Gestational Diabetes
Gestational Diabetes 		Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases 0.010 1.000 1 2017 2017
dbSNP: rs1800544
rs1800544 		0.790 0.160 10 111076745 upstream gene variant G/C snv 0.59
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		Pathological Conditions, Signs and Symptoms; Neoplasms 0.010 1.000 1 2016 2016
dbSNP: rs1800544
rs1800544 		0.790 0.160 10 111076745 upstream gene variant G/C snv 0.59
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone 		Neoplasms 0.010 1.000 1 2015 2015
dbSNP: rs1800544
rs1800544 		0.790 0.160 10 111076745 upstream gene variant G/C snv 0.59
CUI: C0424295
Disease: Hyperactive behavior
Hyperactive behavior 		Pathological Conditions, Signs and Symptoms; Nervous System Diseases 0.010 1.000 1 2010 2010
dbSNP: rs1800544
rs1800544 		0.790 0.160 10 111076745 upstream gene variant G/C snv 0.59
CUI: C0521170
Disease: Osteoporotic Fractures
Osteoporotic Fractures 		Wounds and Injuries 0.010 1.000 1 2018 2018
dbSNP: rs1800544
rs1800544 		0.790 0.160 10 111076745 upstream gene variant G/C snv 0.59
CUI: C1332986
Disease: Childhood Osteosarcoma
Childhood Osteosarcoma 		Neoplasms 0.010 1.000 1 2015 2015
dbSNP: rs1800544
rs1800544 		0.790 0.160 10 111076745 upstream gene variant G/C snv 0.59
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		Neoplasms 0.010 1.000 1 2015 2015
dbSNP: rs1800544
rs1800544 		0.790 0.160 10 111076745 upstream gene variant G/C snv 0.59
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		Mental Disorders 0.010 1.000 1 2013 2013
dbSNP: rs1800544
rs1800544 		0.790 0.160 10 111076745 upstream gene variant G/C snv 0.59
CUI: C0041671
Disease: Attention Deficit Disorder
Attention Deficit Disorder 		Mental Disorders 0.010 1.000 1 2010 2010
dbSNP: rs1800544
rs1800544 		0.790 0.160 10 111076745 upstream gene variant G/C snv 0.59
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.010 1.000 1 2016 2016
dbSNP: rs1800544
rs1800544 		0.790 0.160 10 111076745 upstream gene variant G/C snv 0.59
CUI: C0025517
Disease: Metabolic Diseases
Metabolic Diseases 		Nutritional and Metabolic Diseases 0.010 1.000 1 2016 2016
dbSNP: rs3750625
rs3750625 		10 111079843 3 prime UTR variant C/A snv 8.7E-02
CUI: C0030193
Disease: Pain
Pain 		Pathological Conditions, Signs and Symptoms 0.010 1.000 1 2017 2017
dbSNP: rs3750625
rs3750625 		10 111079843 3 prime UTR variant C/A snv 8.7E-02
CUI: C0085207
Disease: Gestational Diabetes
Gestational Diabetes 		Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases 0.010 1.000 1 2017 2017
dbSNP: rs521674
rs521674 		0.925 0.160 10 111075832 upstream gene variant T/A snv 0.57
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		Chemically-Induced Disorders; Mental Disorders 0.010 1.000 1 2012 2012
dbSNP: rs521674
rs521674 		0.925 0.160 10 111075832 upstream gene variant T/A snv 0.57
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.010 1.000 1 2013 2013
dbSNP: rs553668
rs553668 		0.807 0.160 10 111079821 3 prime UTR variant A/G;T snv
CUI: C0011847
Disease: Diabetes
Diabetes 		Endocrine System Diseases 0.010 1.000 1 2012 2012
dbSNP: rs553668
rs553668 		0.807 0.160 10 111079821 3 prime UTR variant A/G;T snv
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone 		Neoplasms 0.010 1.000 1 2015 2015
dbSNP: rs553668
rs553668 		0.807 0.160 10 111079821 3 prime UTR variant A/G;T snv
CUI: C0025517
Disease: Metabolic Diseases
Metabolic Diseases 		Nutritional and Metabolic Diseases 0.010 1.000 1 2016 2016